Triple
T19157391
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Zetia |
E468959
|
entity |
| Predicate | targets |
P860
|
FINISHED |
| Object | NPC1L1 transporter |
—
|
NE NERFINISHED |
How this triple was built (3 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: NPC1L1 transporter | Statement: [Zetia, targets, NPC1L1 transporter]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: NPC1L1 transporter Context triple: [Zetia, targets, NPC1L1 transporter]
-
A.
ABCG2 gene
The ABCG2 gene encodes a membrane transporter protein involved in multidrug resistance and the efflux of various xenobiotics and endogenous compounds across cellular membranes.
-
B.
APOE gene
The APOE gene encodes apolipoprotein E, a key protein in lipid metabolism whose variants, especially ε4, strongly influence risk for Alzheimer’s disease and cardiovascular disorders.
-
C.
CYP3A5
CYP3A5 is a liver-expressed cytochrome P450 enzyme that metabolizes various drugs and xenobiotics, contributing to interindividual variability in drug clearance.
-
D.
BCRP
BCRP is the Central Reserve Bank of Peru, the country’s monetary authority responsible for maintaining monetary stability and managing its currency and international reserves.
-
E.
BCRP
BCRP (Breast Cancer Resistance Protein) is an ATP-binding cassette (ABC) efflux transporter involved in multidrug resistance and the transport of various drugs and xenobiotics across cellular membranes.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: NPC1L1 transporter Target entity description: The NPC1L1 transporter is an intestinal membrane protein that mediates cholesterol absorption from the gut and is inhibited by the lipid-lowering drug ezetimibe.
-
A.
ABCG2 gene
The ABCG2 gene encodes a membrane transporter protein involved in multidrug resistance and the efflux of various xenobiotics and endogenous compounds across cellular membranes.
-
B.
APOE gene
The APOE gene encodes apolipoprotein E, a key protein in lipid metabolism whose variants, especially ε4, strongly influence risk for Alzheimer’s disease and cardiovascular disorders.
-
C.
CYP3A5
CYP3A5 is a liver-expressed cytochrome P450 enzyme that metabolizes various drugs and xenobiotics, contributing to interindividual variability in drug clearance.
-
D.
BCRP
BCRP is the Central Reserve Bank of Peru, the country’s monetary authority responsible for maintaining monetary stability and managing its currency and international reserves.
-
E.
BCRP
BCRP (Breast Cancer Resistance Protein) is an ATP-binding cassette (ABC) efflux transporter involved in multidrug resistance and the transport of various drugs and xenobiotics across cellular membranes.
- F. None of above. chosen
Provenance (2 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d8dd084ff48190ac0f8c46ee722629 |
completed | April 10, 2026, 11:20 a.m. |
| NER | Named-entity recognition | batch_69e5eeba91a081909c04d61d6117da06 |
completed | April 20, 2026, 9:15 a.m. |
Created at: April 10, 2026, 12:06 p.m.