Triple
T16115574
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Association for Molecular Pathology v. Myriad Genetics, Inc. |
E390992
|
entity |
| Predicate | subjectMatter |
P450
|
FINISHED |
| Object |
BRCA1 gene
The BRCA1 gene is a human tumor suppressor gene whose mutations are strongly associated with increased risk of breast and ovarian cancer and played a central role in legal debates over the patentability of human genes.
|
E1194060
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: BRCA1 gene | Statement: [Association for Molecular Pathology v. Myriad Genetics, Inc., subjectMatter, BRCA1 gene]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: BRCA1 gene Context triple: [Association for Molecular Pathology v. Myriad Genetics, Inc., subjectMatter, BRCA1 gene]
-
A.
ERBB2
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
-
B.
HER2 receptor
The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
-
C.
EGFR
EGFR (epidermal growth factor receptor) is a transmembrane receptor tyrosine kinase that regulates cell growth and survival and is frequently implicated in cancer development and progression.
-
D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
E.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: BRCA1 gene Triple: [Association for Molecular Pathology v. Myriad Genetics, Inc., subjectMatter, BRCA1 gene]
Generated description
The BRCA1 gene is a human tumor suppressor gene whose mutations are strongly associated with increased risk of breast and ovarian cancer and played a central role in legal debates over the patentability of human genes.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: BRCA1 gene Target entity description: The BRCA1 gene is a human tumor suppressor gene whose mutations are strongly associated with increased risk of breast and ovarian cancer and played a central role in legal debates over the patentability of human genes.
-
A.
ERBB2
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
-
B.
HER2 receptor
The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
-
C.
EGFR
EGFR (epidermal growth factor receptor) is a transmembrane receptor tyrosine kinase that regulates cell growth and survival and is frequently implicated in cancer development and progression.
-
D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
E.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d87f1a8dd881909f1de6ef78849874 |
completed | April 10, 2026, 4:39 a.m. |
| NER | Named-entity recognition | batch_69e2016a9dd48190bca3f58778ed865f |
completed | April 17, 2026, 9:46 a.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69ffebab779c8190b466c26f4024aa31 |
completed | May 10, 2026, 2:21 a.m. |
| NEDg | Description generation | batch_69ffec4898088190bed531e33418c7e5 |
completed | May 10, 2026, 2:24 a.m. |
| NED2 | Entity disambiguation (via description) | batch_69ffecce96508190a53f100e3207ebac |
completed | May 10, 2026, 2:26 a.m. |
Created at: April 10, 2026, 5 a.m.