Triple
T15982906
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Vertex Pharmaceuticals |
E387617
|
entity |
| Predicate | hasClinicalProgram |
P6928
|
FINISHED |
| Object |
exagamglogene autotemcel
Exagamglogene autotemcel is an investigational CRISPR/Cas9-based gene-editing therapy being developed to treat inherited blood disorders such as sickle cell disease and transfusion-dependent beta thalassemia.
|
E1188107
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: exagamglogene autotemcel | Statement: [Vertex Pharmaceuticals, hasClinicalProgram, exagamglogene autotemcel]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: exagamglogene autotemcel Context triple: [Vertex Pharmaceuticals, hasClinicalProgram, exagamglogene autotemcel]
-
A.
Kymriah
Kymriah is a pioneering CAR-T cell therapy used to treat certain types of blood cancers by genetically modifying a patient’s own immune cells to target and destroy malignant cells.
-
B.
onasemnogene abeparvovec
Onasemnogene abeparvovec is a gene therapy medication that delivers a functional copy of the SMN1 gene to treat infants and young children with certain forms of spinal muscular atrophy.
-
C.
AveXis
AveXis is a biotechnology company best known for developing the gene therapy onasemnogene abeparvovec (Zolgensma) for spinal muscular atrophy.
-
D.
daratumumab
Daratumumab is a monoclonal antibody drug used primarily to treat multiple myeloma by targeting and destroying malignant plasma cells.
-
E.
isatuximab
Isatuximab is a monoclonal antibody drug used primarily in the treatment of multiple myeloma by targeting and killing malignant plasma cells.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: exagamglogene autotemcel Triple: [Vertex Pharmaceuticals, hasClinicalProgram, exagamglogene autotemcel]
Generated description
Exagamglogene autotemcel is an investigational CRISPR/Cas9-based gene-editing therapy being developed to treat inherited blood disorders such as sickle cell disease and transfusion-dependent beta thalassemia.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: exagamglogene autotemcel Target entity description: Exagamglogene autotemcel is an investigational CRISPR/Cas9-based gene-editing therapy being developed to treat inherited blood disorders such as sickle cell disease and transfusion-dependent beta thalassemia.
-
A.
Kymriah
Kymriah is a pioneering CAR-T cell therapy used to treat certain types of blood cancers by genetically modifying a patient’s own immune cells to target and destroy malignant cells.
-
B.
onasemnogene abeparvovec
Onasemnogene abeparvovec is a gene therapy medication that delivers a functional copy of the SMN1 gene to treat infants and young children with certain forms of spinal muscular atrophy.
-
C.
AveXis
AveXis is a biotechnology company best known for developing the gene therapy onasemnogene abeparvovec (Zolgensma) for spinal muscular atrophy.
-
D.
daratumumab
Daratumumab is a monoclonal antibody drug used primarily to treat multiple myeloma by targeting and destroying malignant plasma cells.
-
E.
isatuximab
Isatuximab is a monoclonal antibody drug used primarily in the treatment of multiple myeloma by targeting and killing malignant plasma cells.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d86da94ccc819083d187f5dc6a123e |
completed | April 10, 2026, 3:25 a.m. |
| NER | Named-entity recognition | batch_69e15755b5548190acfa29eecb11e675 |
completed | April 16, 2026, 9:40 p.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69ffc3cdf7848190848e9081027dc027 |
completed | May 9, 2026, 11:31 p.m. |
| NEDg | Description generation | batch_69ffc5669c1c81909bacf61c96cb7816 |
completed | May 9, 2026, 11:38 p.m. |
| NED2 | Entity disambiguation (via description) | batch_69ffc5c7db1c8190b4e1de6f6e3ce8a0 |
completed | May 9, 2026, 11:39 p.m. |
Created at: April 10, 2026, 4:54 a.m.