Triple

T15478689
Position Surface form Disambiguated ID Type / Status
Subject kynurenine pathway E376854 entity
Predicate rateLimitingEnzyme P118413 FINISHED
Object tryptophan 2,3-dioxygenase E1159681 NE FINISHED

How this triple was built (2 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: tryptophan 2,3-dioxygenase | Statement: [kynurenine pathway, rateLimitingEnzyme, tryptophan 2,3-dioxygenase]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07 
Target entity: tryptophan 2,3-dioxygenase
Context triple: [kynurenine pathway, rateLimitingEnzyme, tryptophan 2,3-dioxygenase]
  • A. tryptophan 2,3-dioxygenase chosen
    Tryptophan 2,3-dioxygenase is a heme-containing enzyme that catalyzes the first and rate-limiting step in the oxidative degradation of tryptophan, playing a key role in tryptophan metabolism and regulation.
  • B. indoleamine 2,3-dioxygenase 2
    Indoleamine 2,3-dioxygenase 2 is an immune-regulatory heme-containing enzyme that catalyzes the oxidative degradation of tryptophan along the kynurenine pathway, influencing inflammation and immune tolerance.
  • C. kynureninase
    Kynureninase is a pyridoxal phosphate-dependent enzyme that catalyzes key steps in tryptophan degradation within the kynurenine pathway, contributing to the production of NAD⁺ and other metabolites.
  • D. kynurenine aminotransferase II
    Kynurenine aminotransferase II is a pyridoxal phosphate-dependent enzyme that converts kynurenine to kynurenic acid, a neuroactive metabolite implicated in brain function and neurodegenerative disorders.
  • E. aromatic L-amino acid decarboxylase
    Aromatic L-amino acid decarboxylase is a pyridoxal phosphate–dependent enzyme that catalyzes the decarboxylation of aromatic L-amino acids to produce key neurotransmitters such as dopamine and serotonin.
  • F. None of above.
  • G. Unsure - the case is ambiguous/there is not enough information to decide.

Provenance (3 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d85cd21dcc81908646251b1c26ea00 completed April 10, 2026, 2:13 a.m.
NER Named-entity recognition batch_69e03f8a77a081909f12f13660452f4a completed April 16, 2026, 1:46 a.m.
NED1 Entity disambiguation (via context triple) batch_69ff36595bfc8190a0d60b3cb875ccc5 completed May 9, 2026, 1:27 p.m.
Created at: April 10, 2026, 3:34 a.m.