Triple

T12172973
Position Surface form Disambiguated ID Type / Status
Subject David Sinclair E290015 entity
Predicate founded P104 FINISHED
Object Sirtris Pharmaceuticals
Sirtris Pharmaceuticals was a biotechnology company focused on developing drugs that target sirtuins and cellular pathways related to aging and metabolic diseases.
E967266 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Sirtris Pharmaceuticals | Statement: [David Sinclair, founded, Sirtris Pharmaceuticals]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: Sirtris Pharmaceuticals
Context triple: [David Sinclair, founded, Sirtris Pharmaceuticals]
  • A. Millennium Pharmaceuticals
    Millennium Pharmaceuticals is a biotechnology company known for developing innovative cancer therapies, including the proteasome inhibitor bortezomib (Velcade) for multiple myeloma.
  • B. Ariad Pharmaceuticals
    Ariad Pharmaceuticals was a biotechnology company focused on developing targeted therapies for cancer and other serious diseases.
  • C. Portola Pharmaceuticals
    Portola Pharmaceuticals is a biopharmaceutical company specializing in the development of therapies for thrombosis and other hematologic conditions.
  • D. Vertex Pharmaceuticals
    Vertex Pharmaceuticals is a biotechnology company best known for developing transformative therapies for cystic fibrosis and other serious diseases using a precision medicine approach.
  • E. Jazz Pharmaceuticals
    Jazz Pharmaceuticals is a biopharmaceutical company specializing in developing and commercializing innovative medicines for sleep disorders, oncology, and rare diseases.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: Sirtris Pharmaceuticals
Triple: [David Sinclair, founded, Sirtris Pharmaceuticals]
Generated description
Sirtris Pharmaceuticals was a biotechnology company focused on developing drugs that target sirtuins and cellular pathways related to aging and metabolic diseases.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: Sirtris Pharmaceuticals
Target entity description: Sirtris Pharmaceuticals was a biotechnology company focused on developing drugs that target sirtuins and cellular pathways related to aging and metabolic diseases.
  • A. Millennium Pharmaceuticals
    Millennium Pharmaceuticals is a biotechnology company known for developing innovative cancer therapies, including the proteasome inhibitor bortezomib (Velcade) for multiple myeloma.
  • B. Ariad Pharmaceuticals
    Ariad Pharmaceuticals was a biotechnology company focused on developing targeted therapies for cancer and other serious diseases.
  • C. Portola Pharmaceuticals
    Portola Pharmaceuticals is a biopharmaceutical company specializing in the development of therapies for thrombosis and other hematologic conditions.
  • D. Vertex Pharmaceuticals
    Vertex Pharmaceuticals is a biotechnology company best known for developing transformative therapies for cystic fibrosis and other serious diseases using a precision medicine approach.
  • E. Jazz Pharmaceuticals
    Jazz Pharmaceuticals is a biopharmaceutical company specializing in developing and commercializing innovative medicines for sleep disorders, oncology, and rare diseases.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d6ab4d6c00819095a9a7c35de83cfb completed April 8, 2026, 7:23 p.m.
NER Named-entity recognition batch_69d915dab42881908e2580c631d4d1cf completed April 10, 2026, 3:23 p.m.
NED1 Entity disambiguation (via context triple) batch_69f5f6a6de3081908e5e0030c081d5a4 completed May 2, 2026, 1:05 p.m.
NEDg Description generation batch_69f603b639208190a284fcd7e88e9d54 completed May 2, 2026, 2:01 p.m.
NED2 Entity disambiguation (via description) batch_69f60491eaec8190a16472fd37740ea0 completed May 2, 2026, 2:05 p.m.
Created at: April 8, 2026, 9:50 p.m.