Triple

T11074234
Position Surface form Disambiguated ID Type / Status
Subject HER2 receptor E261824 entity
Predicate formsHeterodimerWith P6653 FINISHED
Object ERBB3
ERBB3 is a member of the ErbB family of receptor tyrosine kinases that plays a key role in cell signaling, particularly in cancer, often through potent mitogenic and survival pathways.
E902873 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: ERBB3 | Statement: [HER2 receptor, formsHeterodimerWith, ERBB3]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: ERBB3
Context triple: [HER2 receptor, formsHeterodimerWith, ERBB3]
  • A. ERBB2
    ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
  • B. EWSR1
    EWSR1 is a multifunctional RNA-binding protein involved in transcriptional regulation and RNA processing, best known for its role in chromosomal translocations that drive various sarcomas and leukemias.
  • C. HER2 receptor
    The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
  • D. CDK4
    CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
  • E. EGF
    EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: ERBB3
Triple: [HER2 receptor, formsHeterodimerWith, ERBB3]
Generated description
ERBB3 is a member of the ErbB family of receptor tyrosine kinases that plays a key role in cell signaling, particularly in cancer, often through potent mitogenic and survival pathways.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: ERBB3
Target entity description: ERBB3 is a member of the ErbB family of receptor tyrosine kinases that plays a key role in cell signaling, particularly in cancer, often through potent mitogenic and survival pathways.
  • A. ERBB2
    ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
  • B. EWSR1
    EWSR1 is a multifunctional RNA-binding protein involved in transcriptional regulation and RNA processing, best known for its role in chromosomal translocations that drive various sarcomas and leukemias.
  • C. HER2 receptor
    The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
  • D. CDK4
    CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
  • E. EGF
    EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d6aa9983c08190b0ef61603b69feac completed April 8, 2026, 7:20 p.m.
NER Named-entity recognition batch_69d7994e32fc8190a6591d9e82b68f75 completed April 9, 2026, 12:19 p.m.
NED1 Entity disambiguation (via context triple) batch_69e3c8cc77988190aad54f56dbd0f8cf completed April 18, 2026, 6:09 p.m.
NEDg Description generation batch_69e3cefc00148190a1850dc6e31523c3 completed April 18, 2026, 6:35 p.m.
NED2 Entity disambiguation (via description) batch_69e3d014a644819092c76aa02b573ca9 completed April 18, 2026, 6:40 p.m.
Created at: April 8, 2026, 9:26 p.m.