Triple
T10291960
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | warfarin |
E241385
|
entity |
| Predicate | targets |
P860
|
FINISHED |
| Object |
VKORC1
VKORC1 is an enzyme involved in vitamin K recycling that plays a key role in blood clotting and is the primary molecular target of the anticoagulant drug warfarin.
|
E852347
|
NE FINISHED |
How this triple was built (4 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: VKORC1 | Statement: [warfarin, targets, VKORC1]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: VKORC1 Context triple: [warfarin, targets, VKORC1]
-
A.
CYP2C9
CYP2C9 is a liver enzyme of the cytochrome P450 family that plays a key role in metabolizing various drugs, including many nonsteroidal anti-inflammatory agents and anticoagulants.
-
B.
CYP2C19
CYP2C19 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs, including certain antidepressants, proton pump inhibitors, and antiplatelet agents.
-
C.
warfarin
Warfarin is a long-established oral anticoagulant used to prevent and treat blood clots, requiring regular blood monitoring and dose adjustments due to its narrow therapeutic range and numerous drug and food interactions.
-
D.
CYP1A2
CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
-
E.
CYP2D6
CYP2D6 is a highly polymorphic cytochrome P450 enzyme that plays a major role in the metabolism of many drugs, contributing significantly to interindividual variability in drug response.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: VKORC1 Triple: [warfarin, targets, VKORC1]
Generated description
VKORC1 is an enzyme involved in vitamin K recycling that plays a key role in blood clotting and is the primary molecular target of the anticoagulant drug warfarin.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: VKORC1 Target entity description: VKORC1 is an enzyme involved in vitamin K recycling that plays a key role in blood clotting and is the primary molecular target of the anticoagulant drug warfarin.
-
A.
CYP2C9
CYP2C9 is a liver enzyme of the cytochrome P450 family that plays a key role in metabolizing various drugs, including many nonsteroidal anti-inflammatory agents and anticoagulants.
-
B.
CYP2C19
CYP2C19 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs, including certain antidepressants, proton pump inhibitors, and antiplatelet agents.
-
C.
warfarin
Warfarin is a long-established oral anticoagulant used to prevent and treat blood clots, requiring regular blood monitoring and dose adjustments due to its narrow therapeutic range and numerous drug and food interactions.
-
D.
CYP1A2
CYP1A2 is a liver enzyme of the cytochrome P450 family that plays a key role in the metabolism of various drugs and xenobiotics.
-
E.
CYP2D6
CYP2D6 is a highly polymorphic cytochrome P450 enzyme that plays a major role in the metabolism of many drugs, contributing significantly to interindividual variability in drug response.
- F. None of above. chosen
Provenance (5 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69d381aaafc08190af475ef58dc16aba |
completed | April 6, 2026, 9:49 a.m. |
| NER | Named-entity recognition | batch_69d4d2d35f048190a215493acdf1f718 |
completed | April 7, 2026, 9:48 a.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69d6f85dcbac8190a2ac66354010e328 |
completed | April 9, 2026, 12:52 a.m. |
| NEDg | Description generation | batch_69d6fcaee26c8190a19f7d07a63531f6 |
completed | April 9, 2026, 1:11 a.m. |
| NED2 | Entity disambiguation (via description) | batch_69d6fd879ab88190b0a47295f5d7ad4d |
completed | April 9, 2026, 1:14 a.m. |
Created at: April 6, 2026, 11:42 a.m.