lossOfFunctionLeadsTo
P149298
predicate
Indicates that when the function of one entity is reduced or eliminated, it causes or results in a specific effect or outcome in another entity or system.
Observed surface forms (1)
- dysfunctionLeadsTo ×1
Sample triples (6)
| Subject | Object |
|---|---|
| Nav1.1 sodium channel | network hyperexcitability via predicate surface "dysfunctionLeadsTo" ⓘ |
| SMCR8 | abnormal lysosomal accumulation ⓘ |
| SMCR8 | altered mTORC1 signaling ⓘ |
| SMCR8 | impaired autophagy ⓘ |
|
SMN1 gene
surface form:
SMN1
|
degeneration of alpha motor neurons ⓘ |
|
SMN1 gene
surface form:
SMN1
|
reduced SMN protein levels ⓘ |