hypoxic-ischemic encephalopathy
E939681
Hypoxic-ischemic encephalopathy is a type of brain injury caused by reduced oxygen and blood flow, most commonly occurring around the time of birth and often leading to long-term neurological impairments.
All labels observed (1)
| Label | Occurrences |
|---|---|
| hypoxic-ischemic encephalopathy canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T11698345 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: hypoxic-ischemic encephalopathy Context triple: [Lennox-Gastaut syndrome, hasEtiology, hypoxic-ischemic encephalopathy]
-
A.
congenital Zika syndrome
Congenital Zika syndrome is a pattern of birth defects, including severe microcephaly and brain, eye, and joint abnormalities, that occurs in infants exposed to Zika virus during pregnancy.
-
B.
PHHN
PHHN is the ICAO airport code for Hana Airport, a small public airport on the island of Maui in Hawaii.
-
C.
ischemic stroke
Ischemic stroke is a type of stroke caused by an obstruction of blood flow to part of the brain, leading to tissue damage and neurological deficits.
-
D.
HLT
HLT is the stock ticker symbol for Hilton Worldwide Holdings Inc., a major global hospitality company operating a wide portfolio of hotel and resort brands.
-
E.
Binswanger
Binswanger is a Swiss surname most notably associated with psychiatrist Ludwig Binswanger, a pioneer of existential and phenomenological approaches in psychiatry.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: hypoxic-ischemic encephalopathy Target entity description: Hypoxic-ischemic encephalopathy is a type of brain injury caused by reduced oxygen and blood flow, most commonly occurring around the time of birth and often leading to long-term neurological impairments.
-
A.
congenital Zika syndrome
Congenital Zika syndrome is a pattern of birth defects, including severe microcephaly and brain, eye, and joint abnormalities, that occurs in infants exposed to Zika virus during pregnancy.
-
B.
PHHN
PHHN is the ICAO airport code for Hana Airport, a small public airport on the island of Maui in Hawaii.
-
C.
ischemic stroke
Ischemic stroke is a type of stroke caused by an obstruction of blood flow to part of the brain, leading to tissue damage and neurological deficits.
-
D.
HLT
HLT is the stock ticker symbol for Hilton Worldwide Holdings Inc., a major global hospitality company operating a wide portfolio of hotel and resort brands.
-
E.
Binswanger
Binswanger is a Swiss surname most notably associated with psychiatrist Ludwig Binswanger, a pioneer of existential and phenomenological approaches in psychiatry.
- F. None of above. chosen
Statements (58)
| Predicate | Object |
|---|---|
| instanceOf |
brain injury
ⓘ
medical condition ⓘ neonatal encephalopathy ⓘ |
| affects | brain ⓘ |
| canOccurIn |
preterm infants
ⓘ
term infants ⓘ |
| hasAbbreviation | HIE ⓘ |
| hasCause |
perinatal asphyxia
ⓘ
reduced cerebral blood flow ⓘ reduced oxygen supply to the brain ⓘ |
| hasConsequence |
behavioral problems
ⓘ
cerebral palsy ⓘ cognitive impairment ⓘ developmental delay ⓘ epilepsy ⓘ learning disabilities ⓘ motor deficits ⓘ neurological impairment ⓘ |
| hasPrognosis |
higher mortality in severe cases
ⓘ
risk of long-term neurodevelopmental disability ⓘ |
| hasRiskFactor |
fetal distress
ⓘ
maternal hypotension ⓘ placental abruption ⓘ prolonged labor ⓘ severe neonatal hypoglycemia ⓘ severe neonatal hypotension ⓘ severe neonatal sepsis ⓘ umbilical cord prolapse ⓘ uterine rupture ⓘ |
| hasStage |
mild HIE
ⓘ
moderate HIE ⓘ severe HIE ⓘ |
| hasSymptom |
abnormal muscle tone in the newborn
ⓘ
abnormal reflexes in the newborn ⓘ altered level of consciousness in the newborn ⓘ feeding difficulties in the newborn ⓘ respiratory depression in the newborn ⓘ seizures in the newborn ⓘ |
| hasTreatment |
neurodevelopmental follow-up
ⓘ
respiratory support ⓘ seizure management ⓘ supportive intensive care ⓘ therapeutic hypothermia ⓘ |
| isAssociatedWith |
basal ganglia injury
ⓘ
cerebral white matter injury ⓘ cortical injury ⓘ |
| isClassifiedBy | Sarnat staging NERFINISHED ⓘ |
| isDiagnosedBy |
Apgar scores
ⓘ
amplitude-integrated EEG ⓘ brain MRI ⓘ clinical examination of the newborn ⓘ cranial ultrasound ⓘ electroencephalography ⓘ umbilical cord blood gas analysis ⓘ |
| isPreventedBy |
adequate intrapartum fetal monitoring
ⓘ
timely obstetric intervention ⓘ |
| typicallyOccurs |
around the time of birth
GENERATED
ⓘ
perinatal period GENERATED ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: hypoxic-ischemic encephalopathy Description of subject: Hypoxic-ischemic encephalopathy is a type of brain injury caused by reduced oxygen and blood flow, most commonly occurring around the time of birth and often leading to long-term neurological impairments.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.