collie eye anomaly
E938597
Collie eye anomaly is an inherited congenital eye disease in herding dog breeds that can cause vision impairment or blindness due to abnormal development of ocular structures.
Observed surface forms (1)
| Surface form | Occurrences |
|---|---|
| Collie eye anomaly | 0 |
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
canine disease
ⓘ
congenital eye disease ⓘ hereditary eye disorder ⓘ |
| affectedStructure |
choroid
ⓘ
optic disc ⓘ retina ⓘ sclera ⓘ |
| affectsSpecies | dog ⓘ |
| ageOfOnset | present at birth ⓘ |
| alsoKnownAs |
CEA
NERFINISHED
ⓘ
choroidal hypoplasia ⓘ |
| canCause |
blindness
ⓘ
vision impairment ⓘ |
| causativeGene | NHEJ1 NERFINISHED ⓘ |
| causativeMutationType | deletion ⓘ |
| chromosomalLocation | canine chromosome 37 ⓘ |
| classification | non-progressive choroidal hypoplasia in many cases ⓘ |
| congenital | true ⓘ |
| diagnosedBy |
fundus examination
ⓘ
genetic testing ⓘ indirect ophthalmoscopy ⓘ ophthalmic examination ⓘ |
| examTimingRecommendation | eye exam at 6–8 weeks of age ⓘ |
| firstDescribedIn | 20th century ⓘ |
| geographicPrevalence | worldwide in herding breeds ⓘ |
| hereditaryStatus | inherited ⓘ |
| inheritancePattern | autosomal recessive ⓘ |
| managedBy | veterinary ophthalmologist ⓘ |
| modeOfTransmission | both parents must carry mutation for affected offspring ⓘ |
| possibleLesion |
coloboma
ⓘ
intraocular hemorrhage ⓘ retinal detachment ⓘ staphyloma ⓘ |
| preventedBy | selective breeding ⓘ |
| primaryLesion | choroidal hypoplasia GENERATED ⓘ |
| screeningRecommendedFor | breeding dogs in at-risk breeds ⓘ |
| severity |
mild
ⓘ
moderate ⓘ severe ⓘ |
| treatmentForComplications | surgery for retinal detachment in selected cases ⓘ |
| treatmentForMildCases | often not required ⓘ |
| typicalBreed |
Australian Shepherd
GENERATED
ⓘ
Border Collie GENERATED ⓘ Lancashire Heeler GENERATED ⓘ Nova Scotia Duck Tolling Retriever GENERATED ⓘ Rough Collie GENERATED ⓘ Shetland Sheepdog GENERATED ⓘ Smooth Collie GENERATED ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.