bursa of Fabricius in birds
E902893
The bursa of Fabricius in birds is a specialized lymphoid organ near the cloaca that plays a crucial role in the development and maturation of B lymphocytes in avian species.
Observed surface forms (1)
| Surface form | Occurrences |
|---|---|
| bursa of Fabricius | 0 |
Statements (50)
| Predicate | Object |
|---|---|
| instanceOf |
avian organ
ⓘ
lymphoid tissue ⓘ primary lymphoid organ ⓘ |
| absentIn |
amphibians
ⓘ
fish ⓘ mammals ⓘ reptiles ⓘ |
| analogousFunctionTo | bone marrow in mammals ⓘ |
| cellTypeDeveloping | B cells ⓘ |
| connectedTo | cloacal lumen ⓘ |
| contains |
lymphocytes
ⓘ
macrophages ⓘ reticular epithelial cells ⓘ stromal cells ⓘ |
| developmentalOrigin | dorsal diverticulum of the cloaca ⓘ |
| discoveredBy | Hieronymus Fabricius NERFINISHED ⓘ |
| discoveryCentury | 16th century ⓘ |
| drainedBy | lymphatic vessels ⓘ |
| epitheliumType | pseudostratified columnar epithelium ⓘ |
| firstSiteOf |
B cell differentiation in birds
GENERATED
ⓘ
B cell repertoire formation in birds GENERATED ⓘ |
| function |
development of B lymphocytes
ⓘ
generation of antibody-producing cells ⓘ maturation of B lymphocytes ⓘ |
| hasRegion |
follicular cortex
ⓘ
follicular medulla ⓘ mucosal folds ⓘ |
| histologicalFeature | bursa-associated lymphoid follicles ⓘ |
| lesionEffect | immunosuppression in birds ⓘ |
| locatedIn | birds ⓘ |
| locatedNear | cloaca ⓘ |
| macroscopicAppearance | sac-like diverticulum ⓘ |
| namedAfter | Hieronymus Fabricius NERFINISHED ⓘ |
| orientation | dorsal to the cloaca ⓘ |
| partOf | avian immune system ⓘ |
| presentInLifeStage | juvenile birds ⓘ |
| richIn | lymphoid follicles ⓘ |
| roleInImmunity |
diversification of immunoglobulin repertoire
GENERATED
ⓘ
humoral immunity GENERATED ⓘ |
| speciesExample |
chickens
ⓘ
ducks ⓘ pigeons ⓘ turkeys ⓘ |
| susceptibleTo |
Gumboro disease
NERFINISHED
ⓘ
infectious bursal disease virus ⓘ |
| undergoes | involution at sexual maturity ⓘ |
| usedIn | immunological research ⓘ |
| usedToStudy |
B cell ontogeny
ⓘ
avian immunology ⓘ |
| vascularSupply | branches of the cloacal artery ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.