mucosa-associated lymphoid tissue
E902887
Mucosa-associated lymphoid tissue (MALT) is a diffuse system of immune cells and lymphoid structures located in mucosal linings that plays a key role in defending the body against pathogens entering through surfaces such as the gut, respiratory tract, and genitourinary tract.
Statements (50)
| Predicate | Object |
|---|---|
| instanceOf |
component of immune system
ⓘ
lymphoid tissue ⓘ secondary lymphoid organ ⓘ |
| abbreviation | MALT ⓘ |
| associatedWith |
lamina propria
ⓘ
mucosal epithelium ⓘ submucosa ⓘ |
| associatedWithDisease |
MALT lymphoma
NERFINISHED
ⓘ
extranodal marginal zone B-cell lymphoma of MALT type ⓘ |
| associatedWithPathogen | Helicobacter pylori in gastric MALT lymphoma GENERATED ⓘ |
| composedOf |
B lymphocytes
ⓘ
T lymphocytes ⓘ dendritic cells ⓘ innate lymphoid cells ⓘ macrophages ⓘ plasma cells ⓘ |
| developsIn |
postnatal period
ⓘ
response to antigen exposure ⓘ |
| foundInSpecies |
humans
ⓘ
other mammals ⓘ |
| hasFunction |
defense against pathogens entering via mucosal surfaces
ⓘ
induction of adaptive immune responses at mucosal surfaces ⓘ maintenance of mucosal tolerance to commensal microbiota ⓘ maintenance of oral tolerance to dietary antigens ⓘ mucosal immune surveillance ⓘ production of secretory IgA antibodies ⓘ |
| hasPart |
Peyer patches
NERFINISHED
ⓘ
appendix lymphoid tissue ⓘ bronchus-associated lymphoid tissue ⓘ conjunctiva-associated lymphoid tissue NERFINISHED ⓘ gut-associated lymphoid tissue NERFINISHED ⓘ isolated lymphoid follicles ⓘ larynx-associated lymphoid tissue ⓘ nasal-associated lymphoid tissue ⓘ tonsils ⓘ urethra-associated lymphoid tissue ⓘ vulvo-vaginal-associated lymphoid tissue ⓘ |
| locatedIn |
breast tissue mucosa-associated regions
ⓘ
conjunctival mucosa ⓘ gastrointestinal tract mucosa ⓘ genitourinary tract mucosa ⓘ mucosal linings ⓘ respiratory tract mucosa ⓘ salivary gland mucosa ⓘ skin-associated epithelial interfaces ⓘ thyroid gland NERFINISHED ⓘ |
| partOf |
immune system
ⓘ
mucosal immune system ⓘ |
| structureType |
diffuse lymphoid tissue
ⓘ
organized lymphoid follicles ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.