B1 antigen
E902886
B1 antigen is a cell-surface molecule found on most B lymphocytes and is widely used as a diagnostic and therapeutic target in B-cell malignancies.
Statements (27)
| Predicate | Object |
|---|---|
| instanceOf |
B-cell surface marker
ⓘ
cell surface antigen ⓘ diagnostic biomarker ⓘ therapeutic target ⓘ |
| associatedWithDisease |
B-cell leukemia
NERFINISHED
ⓘ
B-cell lymphoma ⓘ |
| biologicalRole |
B-cell identification marker
ⓘ
surface recognition molecule on B cells ⓘ |
| cellularLocation | cell surface ⓘ |
| detectedBy |
flow cytometry
ⓘ
immunohistochemistry ⓘ |
| expressedOn | most B lymphocytes ⓘ |
| expressedPredominantlyIn | B-cell compartment of the immune system ⓘ |
| foundOnCellType |
B cell
ⓘ
B lymphocyte ⓘ |
| relevantToField |
clinical oncology
ⓘ
hematopathology ⓘ immunology ⓘ |
| targetOf | monoclonal antibodies ⓘ |
| usedAsMarkerFor |
B-cell differentiation
ⓘ
B-cell lineage ⓘ B-cell neoplasms ⓘ |
| usedIn |
diagnosis of B-cell malignancies
ⓘ
therapy of B-cell malignancies ⓘ |
| usedTo |
guide targeted therapy in B-cell cancers
ⓘ
identify malignant B cells ⓘ monitor B-cell tumor burden ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.