Clostridioides difficile

E902869
Gram-positive bacterium anaerobic bacterium bacterial species pathogenic bacterium spore-forming bacterium

Clostridioides difficile is a spore-forming, toxin-producing bacterium that commonly causes antibiotic-associated diarrhea and severe colitis in humans.

Try in SPARQL Jump to: Surface forms Statements Elicitation Referenced by

All labels observed (1)

Label Occurrences
Clostridioides difficile canonical 1

Statements (47)

Predicate Object
instanceOf Gram-positive bacterium ⓘ
anaerobic bacterium ⓘ
bacterial species ⓘ
pathogenic bacterium ⓘ
spore-forming bacterium ⓘ
associatedWith healthcare-associated infections ⓘ
hospital outbreaks ⓘ
causes Clostridioides difficile infection ⓘ
antibiotic-associated diarrhea ⓘ
pseudomembranous colitis ⓘ
toxic megacolon ⓘ
class Clostridia NERFINISHED ⓘ
colonizes human colon ⓘ
diagnosedBy nucleic acid amplification test ⓘ
stool culture ⓘ
stool toxin assay ⓘ
environmentalResistance resistant to many disinfectants ⓘ
spores survive for long periods on surfaces ⓘ
family Peptostreptococcaceae NERFINISHED ⓘ
firstDescribedIn 1935 ⓘ
formerName Clostridium difficile NERFINISHED ⓘ
forms endospores ⓘ
genus Clostridioides NERFINISHED ⓘ
gramStain Gram-positive ⓘ
motility motile with peritrichous flagella ⓘ
notableStrain NAP1/BI/027 hypervirulent strain ⓘ
order Eubacteriales NERFINISHED ⓘ
oxygenRequirement obligate anaerobe ⓘ
phylum Bacillota NERFINISHED ⓘ
preventedBy antibiotic stewardship ⓘ
contact precautions in hospitals ⓘ
hand hygiene with soap and water ⓘ
primaryHost human ⓘ
produces TcdA toxin NERFINISHED ⓘ
TcdB toxin ⓘ
binary toxin CDT ⓘ
riskFactor advanced age ⓘ
broad-spectrum antibiotic use ⓘ
prolonged hospitalization ⓘ
proton pump inhibitor use ⓘ
shape rod-shaped ⓘ
taxonRank species ⓘ
transmissionRoute fecal-oral route ⓘ
treatedWith fecal microbiota transplantation ⓘ
fidaxomicin NERFINISHED ⓘ
metronidazole ⓘ
oral vancomycin ⓘ

How these facts were elicited

The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.

Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10.

# Requirements
- If you don't know the subject at all, return an empty list.
- If the subject is not a named entity, return an empty list.
- Include at least one triple where predicate is "instanceOf".
- Do not get too wordy.
- Separate several objects into multiple triples with one object.
Input
Subject: Clostridioides difficile
Description of subject: Clostridioides difficile is a spore-forming, toxin-producing bacterium that commonly causes antibiotic-associated diarrhea and severe colitis in humans.

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

Cepheid → developsTestFor → Clostridioides difficile ⓘ