ScaleS

E902752

ScaleS is an optimized variant of the Scale tissue clearing technique designed to render biological samples highly transparent while better preserving fluorescent signals and tissue structure for advanced 3D imaging.

All labels observed (1)

Label Occurrences
ScaleS canonical 1

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Statements (33)

Predicate Object
instanceOf biological sample preparation method
tissue clearing technique
appliedTo biological tissues
brain tissue
fixed tissue samples
basedOn Scale tissue clearing technique
enables high-resolution volumetric imaging
long-term fluorescence imaging of cleared samples
visualization of fine neural structures
hasAdvantageOver Scale
hasGoal balance tissue transparency and fluorescence retention
minimize tissue swelling and distortion during clearing
hasProperty better tissue morphology preservation compared to Scale
compatible with genetically encoded fluorescent proteins
compatible with immunostaining
high optical transparency
improved fluorescence preservation compared to Scale
hasPurpose preserve fluorescent signals
preserve tissue structure
render biological samples highly transparent
improvesOn signal preservation of fluorescent proteins
structural integrity of cleared tissue
relatedTo CLARITY tissue clearing
CUBIC tissue clearing
ScaleA2
ScaleU2
usedFor advanced 3D imaging
deep tissue imaging
three-dimensional fluorescence microscopy
usedInField connectomics
developmental biology
histology
neuroscience

How these facts were elicited

Referenced by (1)

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