ScaleA2

E902751

ScaleA2 is an improved variant of the Scale tissue clearing method designed to render biological tissues more transparent while better preserving fluorescent signals for high-resolution imaging.

All labels observed (1)

Label Occurrences
ScaleA2 canonical 1

How this entity was disambiguated

Statements (45)

Predicate Object
instanceOf biological sample preparation method
tissue clearing reagent
tissue clearing solution
aimsToMaintain fluorescence intensity over long imaging times
aimsToReduce light scattering in tissues
appliedTo brain tissue
neural tissue
other organ tissues
compatibleWith fluorescent dyes
fluorescent proteins
designedFor biological tissues
developedFor clearing of fixed tissues
developedInContextOf whole‑brain imaging techniques
enables deep tissue imaging
visualization of fine cellular structures
hasAdvantage better fluorescence signal preservation than ScaleA
hasAdvantageOver ScaleA
hasComponent Triton X‑100 NERFINISHED
glycerol
urea
hasProperty aqueous solution
compatible with high‑resolution imaging
high tissue transparency
improved fluorescence preservation
hasPurpose enable high‑resolution imaging
preserve fluorescent signals
render biological tissues more transparent
tissue clearing
improvesUpon Scale
isDocumentedIn peer‑reviewed scientific literature
isPartOf Scale tissue clearing method family
isUsedIn developmental biology research
histology and pathology research
neuroscience research
isVariantOf Scale
operatesAt room temperature or slightly elevated temperature
precedes more recent tissue clearing methods such as CLARITY
more recent tissue clearing methods such as CUBIC
more recent tissue clearing methods such as SeeDB
relatedTo ScaleB
ScaleU2
requires incubation of tissue samples
usedFor fluorescence microscopy
optical imaging of thick tissues
three‑dimensional imaging of tissues

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.