ABC subfamily B
E852337
ABC subfamily B is a group of ATP-binding cassette (ABC) transporters that typically function as membrane proteins involved in the translocation of various molecules across cellular membranes and often contribute to multidrug resistance.
All labels observed (1)
| Label | Occurrences |
|---|---|
| ABC subfamily B canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T10291804 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: ABC subfamily B Context triple: [P-glycoprotein, belongsToSubfamily, ABC subfamily B]
-
A.
ADN
ADN is a European treaty that sets safety and environmental regulations for transporting dangerous goods on inland waterways.
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B.
A-Group
A-Group was an early Nubian archaeological culture in Lower Nubia, known for its distinctive pottery, burial customs, and interactions with predynastic and early dynastic Egypt.
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C.
ABCL
ABCL (Armed Bear Common Lisp) is an implementation of the Common Lisp programming language that runs on the Java Virtual Machine, enabling interoperability with Java code.
-
D.
ENSB
ENSB is the ICAO airport code for Svalbard Airport, Longyear, the main air gateway to the Svalbard archipelago in Norway.
-
E.
ABCO
ABCO is the stock ticker symbol for The Advisory Board Company, a former publicly traded firm that provided research, technology, and consulting services to healthcare and education organizations.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: ABC subfamily B Target entity description: ABC subfamily B is a group of ATP-binding cassette (ABC) transporters that typically function as membrane proteins involved in the translocation of various molecules across cellular membranes and often contribute to multidrug resistance.
-
A.
ADN
ADN is a European treaty that sets safety and environmental regulations for transporting dangerous goods on inland waterways.
-
B.
A-Group
A-Group was an early Nubian archaeological culture in Lower Nubia, known for its distinctive pottery, burial customs, and interactions with predynastic and early dynastic Egypt.
-
C.
ABCL
ABCL (Armed Bear Common Lisp) is an implementation of the Common Lisp programming language that runs on the Java Virtual Machine, enabling interoperability with Java code.
-
D.
ENSB
ENSB is the ICAO airport code for Svalbard Airport, Longyear, the main air gateway to the Svalbard archipelago in Norway.
-
E.
ABCO
ABCO is the stock ticker symbol for The Advisory Board Company, a former publicly traded firm that provided research, technology, and consulting services to healthcare and education organizations.
- F. None of above. chosen
Statements (40)
| Predicate | Object |
|---|---|
| instanceOf |
ATP-binding cassette transporter subfamily
ⓘ
membrane protein family ⓘ protein family ⓘ |
| associatedWith |
chemotherapeutic drug resistance
ⓘ
multidrug resistance ⓘ xenobiotic efflux ⓘ |
| belongsTo | ABC transporter family ⓘ |
| hasAbbreviation | ABCB subfamily ⓘ |
| hasBiologicalProcess |
cellular response to drug
ⓘ
detoxification ⓘ transmembrane transport ⓘ |
| hasCharacteristic |
contain nucleotide-binding domains
ⓘ
contain transmembrane domains ⓘ multispan transmembrane proteins ⓘ |
| hasDomain |
nucleotide-binding domain
ⓘ
transmembrane helix domain ⓘ |
| hasFunction |
ATP-dependent transmembrane transport
ⓘ
bile acid transport ⓘ drug efflux ⓘ lipid transport ⓘ translocation of molecules across cellular membranes ⓘ |
| hasMember |
ABCB1
ⓘ
ABCB11 ⓘ ABCB4 NERFINISHED ⓘ |
| hasMolecularFunction |
ATP binding
ⓘ
ATPase activity ⓘ transmembrane transporter activity ⓘ |
| hasRoleIn |
cellular homeostasis
ⓘ
pharmacokinetics of drugs ⓘ protection against toxic compounds ⓘ |
| locatedIn |
cell membrane
ⓘ
intracellular membranes ⓘ plasma membrane ⓘ |
| partOf | ATP-binding cassette transporter superfamily ⓘ |
| transports |
bile salts
ⓘ
drugs ⓘ endogenous metabolites ⓘ lipids ⓘ xenobiotics ⓘ |
| usesEnergySource | ATP hydrolysis ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: ABC subfamily B Description of subject: ABC subfamily B is a group of ATP-binding cassette (ABC) transporters that typically function as membrane proteins involved in the translocation of various molecules across cellular membranes and often contribute to multidrug resistance.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.