Haldane principle of gas analysis
E834157
The Haldane principle of gas analysis is a foundational concept in respiratory physiology that relates inspired and expired gas concentrations to quantify gas exchange in the lungs.
Statements (44)
| Predicate | Object |
|---|---|
| instanceOf |
concept in respiratory physiology
ⓘ
physiological principle ⓘ |
| appliesTo |
human respiration
ⓘ
pulmonary gas exchange ⓘ |
| assumes |
nitrogen is physiologically inert in the lungs
ⓘ
no net exchange of nitrogen across the alveolar–capillary membrane ⓘ total inspired gas volume equals total expired gas volume when corrected for nitrogen ⓘ |
| componentOf |
Douglas bag method of gas analysis
NERFINISHED
ⓘ
open-circuit spirometry ⓘ standard methods for measuring VO2 and VCO2 ⓘ |
| concerns |
conservation of nitrogen in the respiratory system
ⓘ
mass balance of respiratory gases ⓘ |
| describes |
relationship between inspired and expired gas concentrations
ⓘ
relationship between inspired and expired gas volumes ⓘ |
| enables |
calculation of alveolar ventilation from expired gas
ⓘ
conversion between inspired and expired volume reference conditions in gas analysis ⓘ determination of respiratory exchange ratio ⓘ |
| field |
exercise physiology
ⓘ
pulmonary medicine ⓘ respiratory physiology ⓘ |
| hasKeyVariable |
expired ventilation
ⓘ
fraction of expired nitrogen ⓘ fraction of inspired nitrogen ⓘ inspired ventilation ⓘ |
| historicalOrigin | early 20th century respiratory physiology ⓘ |
| influencedBy | studies of mine and high-altitude respiration by John Scott Haldane ⓘ |
| namedAfter | John Scott Haldane NERFINISHED ⓘ |
| relatedTo |
Fick principle
NERFINISHED
ⓘ
Haldane transformation NERFINISHED ⓘ alveolar gas equation NERFINISHED ⓘ |
| relates |
inspired gas volume to expired gas volume via nitrogen balance
ⓘ
inspired nitrogen fraction to expired nitrogen fraction ⓘ |
| supports |
calculation of carbon dioxide production from expired gas only
ⓘ
calculation of oxygen consumption from expired gas only ⓘ |
| teaches | that nitrogen can be used as a reference gas in respiratory calculations ⓘ |
| usedFor |
calculation of carbon dioxide production
ⓘ
calculation of oxygen uptake ⓘ indirect calorimetry ⓘ metabolic rate estimation ⓘ quantification of gas exchange in the lungs ⓘ |
| usedIn |
assessment of gas exchange efficiency
ⓘ
cardiopulmonary exercise testing ⓘ clinical pulmonary function testing ⓘ research on ventilation–perfusion relationships ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.