Symmetrel
E804596
Symmetrel is a brand-name antiviral and antiparkinsonian medication whose active ingredient is amantadine.
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
antiparkinsonian medication
ⓘ
antiviral medication ⓘ brand-name drug ⓘ |
| belongsTo | human prescription drug ⓘ |
| contraindicatedIn |
known hypersensitivity to amantadine
ⓘ
severe renal impairment without dose adjustment ⓘ |
| developedFrom | amantadine hydrochloride ⓘ |
| hasActiveIngredient | amantadine ⓘ |
| hasAdverseEffect |
confusion
ⓘ
dizziness ⓘ hallucinations ⓘ insomnia ⓘ livedo reticularis ⓘ nausea ⓘ peripheral edema ⓘ |
| hasATCCode |
J05BB01
ⓘ
N04BB01 ⓘ |
| hasChemicalSubstance | amantadine hydrochloride NERFINISHED ⓘ |
| hasDosageForm |
capsule
ⓘ
oral solution ⓘ |
| hasEffect |
reduces Parkinsonian bradykinesia
ⓘ
reduces Parkinsonian rigidity ⓘ reduces levodopa-induced dyskinesia ⓘ |
| hasLegalStatus | prescription-only medicine in many countries ⓘ |
| hasMechanismOfAction |
blocks dopamine reuptake
ⓘ
blocks influenza A M2 ion channel ⓘ increases dopamine release in the central nervous system ⓘ |
| hasOriginCountry | United States NERFINISHED ⓘ |
| hasPharmacologicClass |
adamantane antiviral
ⓘ
dopaminergic agent ⓘ |
| hasPregnancyCategory | C (US, historical) ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| laterApprovedFor |
treatment of Parkinson's disease
ⓘ
treatment of drug-induced extrapyramidal reactions ⓘ |
| mayCause |
anticholinergic-like side effects
ⓘ
impulse control disorders ⓘ orthostatic hypotension ⓘ |
| metabolizedBy | kidney excretion ⓘ |
| requiresCautionIn |
elderly patients
ⓘ
patients with congestive heart failure ⓘ patients with psychiatric disorders ⓘ patients with seizure disorders ⓘ |
| tradeNameOf | amantadine NERFINISHED ⓘ |
| usedAs | adjunct therapy in Parkinson's disease ⓘ |
| usedFor |
treatment of Parkinson's disease
ⓘ
treatment of drug-induced extrapyramidal symptoms ⓘ treatment of influenza A infection ⓘ |
| wasFirstApprovedFor | prophylaxis and treatment of influenza A ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.