The Double Helix (scientific contribution, not the book author)

E78353

The Double Helix is the iconic structural model of DNA, revealing its two-stranded, twisted-ladder configuration that underpins modern molecular biology and genetics.

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Predicate Object
instanceOf DNA structural model
molecular biology concept
scientific model
describes two-stranded structure of DNA
enables development of DNA sequencing methods
development of genetic engineering
development of molecular cloning techniques
understanding of mutation at the molecular level
understanding of recombination at the molecular level
hasBackboneBondType phosphodiester bonds
hasBondType hydrogen bonds between complementary bases
hasComponent two antiparallel polynucleotide strands
hasConsequence explains Chargaff’s rules via base pairing
suggests semi-conservative replication mechanism
hasDiameter about 2 nanometers in B-DNA
hasFeature base pairs perpendicular to helix axis
complementary base pairing
nitrogenous bases on the inside
sugar-phosphate backbone on the outside
hasFunction explains mechanism of DNA replication
explains mechanism of genetic information storage
provides basis for understanding genetic inheritance
provides framework for molecular genetics
hasHistoricalImpact founded modern molecular biology
revolutionized genetics
hasPitch about 10 base pairs per turn in B-DNA
hasProperty antiparallel strand orientation (5′ to 3′ and 3′ to 5′)
hasShape right-handed helix
hasStructuralFeature major groove
minor groove
involvesBasePair adenine–thymine base pair
guanine–cytosine base pair
isAssociatedWith The Double Helix (scientific contribution, not the book author) self-linksurface differs
surface form: Watson–Crick model of DNA

central dogma of molecular biology
isBasedOn X-ray diffraction data of DNA fibers
isCanonicalFormOf DNA
surface form: B-form DNA
isIconicIn biochemistry
biological sciences
isTaughtIn genetics education
molecular biology education
represents three-dimensional structure of DNA
symbolizes genetic information
modern molecular biology
underpins biotechnology
genomics
structural biology of nucleic acids

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Referenced by (7)

Full triples — surface form annotated when it differs from this entity's canonical label.

Francis Crick notableWork The Double Helix (scientific contribution, not the book author)
James Watson knownFor The Double Helix (scientific contribution, not the book author)
this entity surface form: The Double Helix (book)
James Watson notableWork The Double Helix (scientific contribution, not the book author)
this entity surface form: The Double Helix: A Personal Account of the Discovery of the Structure of DNA
Time magazine Top 100 non-fiction books since 1923 hasPart The Double Helix (scientific contribution, not the book author)
this entity surface form: The Double Helix
The Double Helix (scientific contribution, not the book author) isAssociatedWith The Double Helix (scientific contribution, not the book author) self-linksurface differs
subject surface form: The Double Helix
this entity surface form: Watson–Crick model of DNA
X-ray diffraction images of DNA contributedTo The Double Helix (scientific contribution, not the book author)
this entity surface form: Watson and Crick DNA model
Photo 51 influenced The Double Helix (scientific contribution, not the book author)
this entity surface form: Watson and Crick DNA model