essential amino acid tryptophan
E77872
Essential amino acid tryptophan is a vital nutrient that humans must obtain from their diet and that serves as a biochemical precursor to important molecules such as serotonin, melatonin, and niacin.
Aliases (1)
- tryptophan ×49
Statements (49)
| Predicate | Object |
|---|---|
| instanceOf |
aromatic amino acid
→
essential amino acid → proteinogenic amino acid → α-amino acid → |
| absorbsUVLightAt |
280 nm
→
|
| affects |
mood regulation via serotonin
→
sleep-wake cycle via melatonin → |
| belongsToBiosyntheticFamily |
shikimate pathway in microorganisms and plants
→
|
| cannotBeSynthesizedBy |
humans
→
|
| chemicalFormula |
C11H12N2O2
→
|
| contributesTo |
protein synthesis
→
|
| hasAromaticRing |
indole ring
→
|
| hasChirality |
L-configuration in proteins
→
|
| hasIUPACName |
(2S)-2-amino-3-(1H-indol-3-yl)propanoic acid
→
|
| hasOneLetterCode |
W
→
|
| haspKa |
approximately 2.4 for the carboxyl group
→
approximately 9.4 for the amino group → |
| hasSideChain |
indole group
→
|
| hasStandardGeneticCodeNumber |
amino acid number 11 in many lists
→
|
| hasThreeLetterCode |
Trp
→
|
| isAbundantInFood |
cheese
→
chicken → eggs → fish → milk → nuts → seeds → soybeans → turkey → |
| isEncodedByCodon |
UGG
→
|
| isEssentialFor |
humans
→
many animals → |
| isFoundIn |
dietary proteins
→
|
| isHydrophobic |
true
→
|
| isMetabolizedPrimarilyIn |
liver
→
|
| isPrecursorOf |
NAD+
→
NADP+ → kynurenine → melatonin → niacin → serotonin → tryptamine → |
| mustBeObtainedFrom |
diet
→
|
| participatesInPathway |
NAD+ biosynthesis
→
kynurenine pathway → melatonin biosynthesis → serotonin biosynthesis → |
| wasFirstIsolatedBy |
Frederick Hopkins
→
|
| wasFirstIsolatedInYear |
1901
→
|
Referenced by (1)
| Subject (surface form when different) | Predicate |
|---|---|
|
Frederick Gowland Hopkins
→
|
discovered |