Naegleria fowleri
E728806
Naegleria fowleri is a free-living, thermophilic amoeba known for causing rare but often fatal brain infections in humans, commonly called "brain-eating amoeba" disease.
Statements (83)
| Predicate | Object |
|---|---|
| instanceOf |
free-living amoeba
ⓘ
species of amoeboflagellate protist ⓘ thermophilic organism ⓘ |
| abbreviation | PAM ⓘ |
| biosafetyLevel | BSL-2 or higher in laboratory handling ⓘ |
| canSurviveTemperatureUpTo | 46 °C ⓘ |
| caseFatalityRate | over 95 percent ⓘ |
| causes | primary amoebic meningoencephalitis ⓘ |
| cellType | unicellular ⓘ |
| class | Heterolobosea NERFINISHED ⓘ |
| commonName | brain-eating amoeba ⓘ |
| diagnosisMethod |
PCR testing of cerebrospinal fluid
ⓘ
microscopic examination of cerebrospinal fluid ⓘ |
| discoveredBy | Malcolm Fowler NERFINISHED ⓘ |
| diseaseCourse | rapidly progressive ⓘ |
| diseaseDuration | usually 3 to 7 days after symptom onset ⓘ |
| diseaseOnset | acute ⓘ |
| domain |
Eukarya
ⓘ
surface form:
Eukaryota
|
| earlySymptoms |
fever
ⓘ
headache ⓘ nausea ⓘ vomiting ⓘ |
| family | Vahlkampfiidae NERFINISHED ⓘ |
| feedingType | phagocytosis of bacteria ⓘ |
| genus | Naegleria NERFINISHED ⓘ |
| geographicDistribution | worldwide in suitable warm freshwater environments ⓘ |
| habitat |
geothermal water
ⓘ
hot springs ⓘ lakes ⓘ poorly chlorinated swimming pools ⓘ rivers ⓘ soil ⓘ warm freshwater ⓘ water heaters ⓘ |
| incubationPeriod | 1 to 9 days ⓘ |
| infectiveStage | trophozoite ⓘ |
| infects |
humans
ⓘ
other mammals ⓘ |
| laterSymptoms |
coma
ⓘ
confusion ⓘ seizures ⓘ stiff neck ⓘ |
| lifeCycleStage |
cyst
ⓘ
flagellate ⓘ trophozoite ⓘ |
| mostCasesReportedIn |
Australia
NERFINISHED
ⓘ
India NERFINISHED ⓘ Pakistan NERFINISHED ⓘ United States NERFINISHED ⓘ |
| motilityType |
amoeboid movement
ⓘ
flagellar movement ⓘ |
| namedAfter | Malcolm Fowler NERFINISHED ⓘ |
| notTransmittedBy |
drinking contaminated water
ⓘ
person-to-person contact ⓘ |
| optimalGrowthTemperature | 42 °C ⓘ |
| order | Schizopyrenida NERFINISHED ⓘ |
| oxygenRequirement | aerobic ⓘ |
| pathogenicMechanism |
destruction of brain tissue
ⓘ
induction of inflammation in the central nervous system ⓘ |
| phylum | Percolozoa NERFINISHED ⓘ |
| portalOfEntry |
nasal cavity
ⓘ
olfactory neuroepithelium ⓘ |
| preventionMethod |
avoiding warm freshwater entering the nose
ⓘ
proper chlorination of swimming pools ⓘ using nose clips in warm freshwater ⓘ |
| primaryInfectionSite |
brain
ⓘ
central nervous system ⓘ |
| reproduction | asexual reproduction ⓘ |
| reproductionMode | binary fission ⓘ |
| riskFactor |
swimming or diving in warm freshwater
ⓘ
use of untreated tap water for nasal irrigation ⓘ |
| riskGroup |
children
ⓘ
young adults ⓘ |
| sensitiveTo | amphotericin B in vitro ⓘ |
| taxonRank | species ⓘ |
| temperaturePreference | thermophilic ⓘ |
| transmissionRoute | inhalation of contaminated water through the nose ⓘ |
| treatmentOption |
amphotericin B
NERFINISHED
ⓘ
azithromycin ⓘ fluconazole NERFINISHED ⓘ miltefosine ⓘ rifampin NERFINISHED ⓘ |
| yearDescribed | 1965 ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.