Haldane’s cost of selection
E725887
Haldane’s cost of selection is a population genetics concept quantifying the reproductive burden and time required for natural selection to replace one gene variant with a fitter alternative in a population.
Statements (37)
| Predicate | Object |
|---|---|
| instanceOf |
evolutionary biology concept
ⓘ
population genetics concept ⓘ |
| addresses |
constraints on simultaneous substitutions at many loci
ⓘ
trade-off between selection intensity and population viability ⓘ |
| alsoKnownAs |
cost of natural selection
ⓘ
substitutional load ⓘ |
| appliesTo | replacement of one gene variant by a fitter alternative ⓘ |
| assumes | finite reproductive excess in populations ⓘ |
| concerns |
limits on speed of natural selection
ⓘ
rate of adaptive evolution ⓘ |
| definedBy | J. B. S. Haldane NERFINISHED ⓘ |
| field |
evolutionary theory
ⓘ
population genetics ⓘ |
| historicalContext | mid-20th century population genetics ⓘ |
| implies | upper bound on rate of gene substitutions ⓘ |
| influenced |
later work on genetic load
ⓘ
theoretical limits on adaptive evolution in large populations ⓘ |
| involves |
allele frequency change over time
ⓘ
mortality due to selection ⓘ population size ⓘ reproductive rate ⓘ selection coefficient ⓘ |
| mathematicallyCharacterizedAs | cumulative number of selective deaths needed for allele fixation ⓘ |
| quantifies |
number of selective deaths required for gene substitution
ⓘ
reproductive burden of selection ⓘ time required for a fitter allele to replace a less fit allele ⓘ |
| relatedConcept |
Haldane’s dilemma
NERFINISHED
ⓘ
adaptive substitution rate ⓘ genetic drift ⓘ genetic substitution ⓘ selective sweep ⓘ |
| relatesTo |
fixation of advantageous alleles
ⓘ
genetic load ⓘ selective deaths ⓘ |
| usedIn |
arguments about limits to adaptive evolution
ⓘ
debates on feasibility of rapid evolution ⓘ discussions of molecular evolution rates ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.