Goldman–Hodgkin–Katz equation
E700591
The Goldman–Hodgkin–Katz equation is a biophysical formula that calculates a cell’s membrane potential by accounting for the relative permeabilities and concentrations of multiple ion species across the membrane.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Goldman–Hodgkin–Katz equation canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T7903600 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Goldman–Hodgkin–Katz equation Context triple: [Nernst equation, relatedTo, Goldman–Hodgkin–Katz equation]
-
A.
Hodgkin–Huxley model
The Hodgkin–Huxley model is a mathematical description of how action potentials in neurons are initiated and propagated through voltage-gated ion channels in the cell membrane.
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B.
Randles–Ševčík equation
The Randles–Ševčík equation is a fundamental electrochemical relationship that links peak current in cyclic voltammetry to the concentration and diffusion coefficient of a redox-active species.
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C.
Butler–Volmer equation
The Butler–Volmer equation is a fundamental relation in electrochemistry that describes how the rate of an electrode reaction (current density) depends on the electrode potential and reaction kinetics.
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D.
Nernst–Planck equation
The Nernst–Planck equation is a fundamental relation in electrochemistry that describes the flux of charged species under the combined influence of diffusion, electric fields, and, in extended forms, convection.
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E.
Nernst equation
The Nernst equation is a fundamental electrochemistry formula that relates the reduction potential of a half-cell to the standard electrode potential, temperature, and activities (or concentrations) of the chemical species involved.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Goldman–Hodgkin–Katz equation Target entity description: The Goldman–Hodgkin–Katz equation is a biophysical formula that calculates a cell’s membrane potential by accounting for the relative permeabilities and concentrations of multiple ion species across the membrane.
-
A.
Hodgkin–Huxley model
The Hodgkin–Huxley model is a mathematical description of how action potentials in neurons are initiated and propagated through voltage-gated ion channels in the cell membrane.
-
B.
Randles–Ševčík equation
The Randles–Ševčík equation is a fundamental electrochemical relationship that links peak current in cyclic voltammetry to the concentration and diffusion coefficient of a redox-active species.
-
C.
Butler–Volmer equation
The Butler–Volmer equation is a fundamental relation in electrochemistry that describes how the rate of an electrode reaction (current density) depends on the electrode potential and reaction kinetics.
-
D.
Nernst–Planck equation
The Nernst–Planck equation is a fundamental relation in electrochemistry that describes the flux of charged species under the combined influence of diffusion, electric fields, and, in extended forms, convection.
-
E.
Nernst equation
The Nernst equation is a fundamental electrochemistry formula that relates the reduction potential of a half-cell to the standard electrode potential, temperature, and activities (or concentrations) of the chemical species involved.
- F. None of above. chosen
Statements (47)
| Predicate | Object |
|---|---|
| instanceOf |
biophysical equation
ⓘ
electrophysiology concept ⓘ membrane potential equation ⓘ |
| accountsFor |
extracellular ion concentrations
ⓘ
intracellular ion concentrations ⓘ multiple ion species ⓘ relative ion permeabilities ⓘ |
| alternativeName |
GHK equation
NERFINISHED
ⓘ
Goldman equation in constant-field form NERFINISHED ⓘ |
| appliesTo |
biological membranes
ⓘ
excitable cells ⓘ muscle cells ⓘ neurons ⓘ |
| assumes | constant electric field across the membrane ⓘ |
| basedOn | Goldman equation NERFINISHED ⓘ |
| calculates | membrane potential ⓘ |
| category |
electrochemical gradient equations
ⓘ
ion transport models ⓘ |
| describes |
membrane potential under steady-state conditions
ⓘ
resting membrane potential ⓘ |
| developedInPeriod | mid 20th century ⓘ |
| expressedIn | volts ⓘ |
| field |
biophysics
ⓘ
cell physiology ⓘ neuroscience ⓘ |
| generalizes | Nernst equation NERFINISHED ⓘ |
| mathematicalForm | logarithmic ⓘ |
| namedAfter |
Alan Lloyd Hodgkin
NERFINISHED
ⓘ
Bernard Katz NERFINISHED ⓘ David E. Goldman NERFINISHED ⓘ |
| relatedTo | Nernst equation NERFINISHED ⓘ |
| typicallyIncludesIon |
chloride ion
ⓘ
potassium ion ⓘ sodium ion ⓘ |
| usedFor |
analyzing ion channel selectivity
ⓘ
interpreting patch-clamp data ⓘ modeling resting potential ⓘ |
| usedIn |
Hodgkin–Huxley model
NERFINISHED
ⓘ
computational neuroscience models ⓘ textbooks of neuroscience ⓘ textbooks of physiology ⓘ |
| usesQuantity |
Faraday constant
NERFINISHED
ⓘ
absolute temperature ⓘ gas constant ⓘ ion concentration ⓘ ion permeability ⓘ valence of ions ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Goldman–Hodgkin–Katz equation Description of subject: The Goldman–Hodgkin–Katz equation is a biophysical formula that calculates a cell’s membrane potential by accounting for the relative permeabilities and concentrations of multiple ion species across the membrane.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.