Botox (therapeutic and cosmetic)

E697100

Botox (therapeutic and cosmetic) is a widely used botulinum toxin–based injectable treatment employed both medically to manage conditions like muscle spasticity and migraines and cosmetically to reduce the appearance of facial wrinkles.

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Label Occurrences
Botox (therapeutic and cosmetic) canonical 1

Statements (51)

Predicate Object
instanceOf botulinum toxin type A preparation
cosmetic treatment
injectable medication
therapeutic biologic product
activeIngredient onabotulinumtoxinA
boxedWarning toxin effects may spread beyond injection site
commonAdverseEffect headache
injection site pain
localized muscle weakness
contraindication infection at proposed injection site
known hypersensitivity to botulinum toxin
derivedFrom Clostridium botulinum toxin type A
durationOfEffect typically 3 to 4 months
effect reduction of dynamic wrinkles
temporary muscle relaxation
hasCosmeticUse facial wrinkle reduction
treatment of forehead lines
treatment of glabellar lines
treatment of lateral canthal lines
hasMedicalUse treatment of axillary hyperhidrosis
treatment of blepharospasm
treatment of cervical dystonia
treatment of chronic migraine
treatment of lower limb spasticity
treatment of muscle spasticity
treatment of overactive bladder
treatment of strabismus
treatment of upper limb spasticity
treatment of urinary incontinence due to neurologic conditions
hasPrimaryUse reduction of facial wrinkles
hasRegulatoryStatus prescription only medicine in many countries
hasRouteOfAdministration intradermal injection
intradetrusor injection
intramuscular injection
isAdministeredBy licensed healthcare professional
nurse practitioner
physician
physician assistant
isAdministeredIn outpatient setting
isApprovedBy U.S. Food and Drug Administration NERFINISHED
isManufacturedBy Allergan NERFINISHED
isTradeNameOf onabotulinumtoxinA NERFINISHED
isUsedFor both therapeutic and cosmetic indications
mechanismOfAction inhibition of acetylcholine release at neuromuscular junctions
temporary chemodenervation of muscles
onsetOfAction typically within 3 to 7 days
peakEffectTime about 2 weeks after injection
requires prescription
repeated treatments to maintain effect
seriousAdverseEffect dysphagia
respiratory compromise

Referenced by (1)

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AbbVie notableProduct Botox (therapeutic and cosmetic)