Molecular Evolutionary Clock

E612271

Molecular Evolutionary Clock is a foundational concept in evolutionary biology that uses the rate of genetic mutations to estimate the timing of species divergence and evolutionary events.

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Molecular evolutionary clock 0

Statements (49)

Predicate Object
instanceOf concept in evolutionary biology
dating technique in biology
method in molecular evolution
aimsTo estimate timing of evolutionary events
estimate timing of species divergence
appliedIn studies of biodiversity and speciation
studies of human evolution
studies of viral evolution
appliesTo genes
genomes
proteins
assumes lineages diverge at measurable molecular rates
mutations accumulate over time
basedOn assumption of approximately constant mutation rate
molecular sequence comparisons
calibratedWith biogeographic events
fossil record
known historical divergence times
contrastsWith morphological dating alone
developedInContextOf molecular evolution theory
field evolutionary biology
molecular evolution
hasVariant local molecular clock
relaxed molecular clock
strict molecular clock
helpsExplain tempo of molecular evolution
helpsIntegrate molecular data with fossil data
influencedBy generation time
mutation rate variation among lineages
population size
selection pressures
modeledBy Bayesian methods
maximum likelihood methods
relatedTo comparative genomics
divergence time estimation
molecular phylogeny
phylogenetic trees
phylogenetics
requires sequence alignment
substitution models
supports reconstruction of evolutionary timelines
usedFor dating lineage splits
dating speciation events
estimating time to most recent common ancestor
testing evolutionary hypotheses
uses DNA sequence data
nucleotide substitution rates
protein sequence data
rate of genetic mutations

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Full triples — surface form annotated when it differs from this entity's canonical label.

Motoo Kimura notableWork Molecular Evolutionary Clock