Eylea

E579609
biologic drug ophthalmic drug pharmaceutical drug

Eylea is a widely used injectable drug for treating retinal diseases such as wet age-related macular degeneration by inhibiting vascular endothelial growth factor (VEGF).

Try in SPARQL Jump to: Statements Referenced by

Statements (48)

Predicate Object
instanceOf biologic drug ⓘ
ophthalmic drug ⓘ
pharmaceutical drug ⓘ
hasAdverseEffect cataract ⓘ
conjunctival hemorrhage ⓘ
endophthalmitis ⓘ
eye pain ⓘ
increased intraocular pressure ⓘ
intraocular inflammation ⓘ
retinal detachment ⓘ
thromboembolic events ⓘ
vitreous detachment ⓘ
hasATCCode S01LA05 ⓘ
hasContraindication active intraocular inflammation ⓘ
hypersensitivity to aflibercept ⓘ
ocular or periocular infection ⓘ
hasDosageForm solution for injection ⓘ
hasGenericName aflibercept ⓘ
hasIndication diabetic macular edema ⓘ
macular edema following retinal vein occlusion ⓘ
myopic choroidal neovascularization ⓘ
neovascular age-related macular degeneration ⓘ
wet age-related macular degeneration ⓘ
hasMechanismOfAction VEGF-A binding ⓘ
placental growth factor binding ⓘ
vascular endothelial growth factor inhibitor ⓘ
hasMolecularType fusion protein ⓘ
hasPharmacologicalClass angiogenesis inhibitor ⓘ
recombinant fusion protein ⓘ
hasRegulatoryApproval European Medicines Agency NERFINISHED ⓘ
U.S. Food and Drug Administration NERFINISHED ⓘ
hasRouteOfAdministration intraocular ⓘ
intravitreal injection ⓘ
hasTherapeuticArea ophthalmology ⓘ
retinal vascular disease ⓘ
hasYearOfFirstApproval 2011 ⓘ
isAdministeredBy ophthalmologist ⓘ
isAdministeredFrequency every 4 weeks during initial phase ⓘ
every 8 weeks during maintenance phase ⓘ
isManufacturedBy Regeneron Pharmaceuticals NERFINISHED ⓘ
isMarketedBy Bayer NERFINISHED ⓘ
Regeneron Pharmaceuticals NERFINISHED ⓘ
isUsedFor prevention of vision loss ⓘ
reduction of macular edema ⓘ
treatment of retinal diseases ⓘ
targets VEGF-A NERFINISHED ⓘ
VEGF-B NERFINISHED ⓘ
placental growth factor ⓘ

Referenced by (2)

Full triples — surface form annotated when it differs from this entity's canonical label.

Regeneron Pharmaceuticals → notableProduct → Eylea ⓘ
aflibercept → hasTradeName → Eylea ⓘ