Mectizan
E579606
Mectizan is the brand name for ivermectin, a medication widely used to prevent and treat river blindness (onchocerciasis) and certain other parasitic infections.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Mectizan canonical | 2 |
How this entity was disambiguated
This entity first appeared as the object of triple T6251115 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Mectizan Context triple: [Decision to provide ivermectin (Mectizan) free of charge for river blindness, hasBrandName, Mectizan]
-
A.
pyrantel pamoate
Pyrantel pamoate is an anthelmintic medication commonly used to treat intestinal worm infections such as pinworm, roundworm, and hookworm in humans.
-
B.
albendazole
Albendazole is a broad-spectrum anthelmintic medication commonly used to treat a variety of parasitic worm infections in humans.
-
C.
Plaxtol
Plaxtol is a small rural village and civil parish in Kent, England, known for its historic buildings and surrounding countryside.
-
D.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
-
E.
Doxato
Doxato is a town in northern Greece located within the Drama regional unit, known for its agricultural surroundings and historical significance.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Mectizan Target entity description: Mectizan is the brand name for ivermectin, a medication widely used to prevent and treat river blindness (onchocerciasis) and certain other parasitic infections.
-
A.
pyrantel pamoate
Pyrantel pamoate is an anthelmintic medication commonly used to treat intestinal worm infections such as pinworm, roundworm, and hookworm in humans.
-
B.
albendazole
Albendazole is a broad-spectrum anthelmintic medication commonly used to treat a variety of parasitic worm infections in humans.
-
C.
Plaxtol
Plaxtol is a small rural village and civil parish in Kent, England, known for its historic buildings and surrounding countryside.
-
D.
Opekta
Opekta was a German-Dutch company that produced and sold pectin-based gelling agents for making jam, notably managed in its Amsterdam branch by Anne Frank’s father, Otto Frank.
-
E.
Doxato
Doxato is a town in northern Greece located within the Drama regional unit, known for its agricultural surroundings and historical significance.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand name
ⓘ
pharmaceutical drug ⓘ |
| actsOn | parasites ⓘ |
| adverseEffectRelatedTo | Mazzotti reaction in onchocerciasis ⓘ |
| ATCCode | P02CF01 (ivermectin) ⓘ |
| commonAdverseEffect |
fever
ⓘ
headache ⓘ itching ⓘ rash ⓘ |
| contraindication | known hypersensitivity to ivermectin ⓘ |
| developedBy | Merck & Co. NERFINISHED ⓘ |
| distributedBy | Mectizan Donation Program NERFINISHED ⓘ |
| donatedFor |
lymphatic filariasis elimination programs
ⓘ
onchocerciasis control programs ⓘ |
| drugClass |
anthelmintic
ⓘ
antiparasitic ⓘ |
| effect | causes paralysis and death of susceptible parasites ⓘ |
| hasActiveIngredient | ivermectin ⓘ |
| hasDosageForm |
oral tablet
ⓘ
oral tablet for mass drug administration ⓘ |
| hasFormulationStrength |
3 mg tablet
ⓘ
6 mg tablet ⓘ |
| indication |
control of onchocerciasis transmission
ⓘ
prevention of onchocerciasis-related blindness ⓘ |
| legalStatus | prescription drug in many countries ⓘ |
| manufacturer | Merck & Co. NERFINISHED ⓘ |
| mechanismOfAction | binds to glutamate-gated chloride channels in invertebrate nerve and muscle cells ⓘ |
| pregnancyCategory | use with caution; risk–benefit assessment required ⓘ |
| programAssociatedWith | Mectizan Donation Program NERFINISHED ⓘ |
| publicHealthRole |
key medicine in global onchocerciasis control
ⓘ
key medicine in lymphatic filariasis elimination ⓘ |
| regimenType | mass drug administration ⓘ |
| routeOfAdministration | oral ⓘ |
| storageCondition | store at room temperature ⓘ |
| targetOrganism | Onchocerca volvulus microfilariae ⓘ |
| targetPopulation |
people living in lymphatic filariasis-endemic areas
ⓘ
people living in onchocerciasis-endemic areas ⓘ |
| tradeNameOf | ivermectin ⓘ |
| typicalDosingRegimen | single oral dose given annually or semiannually in mass drug administration ⓘ |
| usedFor |
lymphatic filariasis
ⓘ
onchocerciasis ⓘ other parasitic infections ⓘ river blindness ⓘ scabies ⓘ strongyloidiasis ⓘ |
| worldRegionOfUse |
Africa
NERFINISHED
ⓘ
Latin America NERFINISHED ⓘ Yemen NERFINISHED ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Mectizan Description of subject: Mectizan is the brand name for ivermectin, a medication widely used to prevent and treat river blindness (onchocerciasis) and certain other parasitic infections.
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.