Mectizan
E579606
Mectizan is the brand name for ivermectin, a medication widely used to prevent and treat river blindness (onchocerciasis) and certain other parasitic infections.
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand name
ⓘ
pharmaceutical drug ⓘ |
| actsOn | parasites ⓘ |
| adverseEffectRelatedTo | Mazzotti reaction in onchocerciasis ⓘ |
| ATCCode | P02CF01 (ivermectin) ⓘ |
| commonAdverseEffect |
fever
ⓘ
headache ⓘ itching ⓘ rash ⓘ |
| contraindication | known hypersensitivity to ivermectin ⓘ |
| developedBy | Merck & Co. NERFINISHED ⓘ |
| distributedBy | Mectizan Donation Program NERFINISHED ⓘ |
| donatedFor |
lymphatic filariasis elimination programs
ⓘ
onchocerciasis control programs ⓘ |
| drugClass |
anthelmintic
ⓘ
antiparasitic ⓘ |
| effect | causes paralysis and death of susceptible parasites ⓘ |
| hasActiveIngredient | ivermectin ⓘ |
| hasDosageForm |
oral tablet
ⓘ
oral tablet for mass drug administration ⓘ |
| hasFormulationStrength |
3 mg tablet
ⓘ
6 mg tablet ⓘ |
| indication |
control of onchocerciasis transmission
ⓘ
prevention of onchocerciasis-related blindness ⓘ |
| legalStatus | prescription drug in many countries ⓘ |
| manufacturer | Merck & Co. NERFINISHED ⓘ |
| mechanismOfAction | binds to glutamate-gated chloride channels in invertebrate nerve and muscle cells ⓘ |
| pregnancyCategory | use with caution; risk–benefit assessment required ⓘ |
| programAssociatedWith | Mectizan Donation Program NERFINISHED ⓘ |
| publicHealthRole |
key medicine in global onchocerciasis control
ⓘ
key medicine in lymphatic filariasis elimination ⓘ |
| regimenType | mass drug administration ⓘ |
| routeOfAdministration | oral ⓘ |
| storageCondition | store at room temperature ⓘ |
| targetOrganism | Onchocerca volvulus microfilariae ⓘ |
| targetPopulation |
people living in lymphatic filariasis-endemic areas
ⓘ
people living in onchocerciasis-endemic areas ⓘ |
| tradeNameOf | ivermectin ⓘ |
| typicalDosingRegimen | single oral dose given annually or semiannually in mass drug administration ⓘ |
| usedFor |
lymphatic filariasis
ⓘ
onchocerciasis ⓘ other parasitic infections ⓘ river blindness ⓘ scabies ⓘ strongyloidiasis ⓘ |
| worldRegionOfUse |
Africa
NERFINISHED
ⓘ
Latin America NERFINISHED ⓘ Yemen NERFINISHED ⓘ |
Referenced by (2)
Full triples — surface form annotated when it differs from this entity's canonical label.