Plavix
E561776
Plavix is a widely used prescription antiplatelet medication (clopidogrel) that helps prevent blood clots and reduce the risk of heart attack and stroke.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Plavix canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T6006201 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Plavix Context triple: [Sanofi, hasBrand, Plavix]
-
A.
Brilinta
Brilinta is a prescription antiplatelet medication (ticagrelor) used to reduce the risk of heart attack, stroke, and cardiovascular death in patients with acute coronary syndrome or a history of myocardial infarction.
-
B.
Xarelto
Xarelto is a widely used prescription anticoagulant (blood thinner) that helps prevent and treat blood clots and reduce the risk of stroke in certain patients.
-
C.
Lipitor
Lipitor is a widely prescribed statin medication used to lower cholesterol and reduce the risk of cardiovascular disease.
-
D.
dabigatran
Dabigatran is an oral direct thrombin inhibitor anticoagulant used to prevent and treat blood clots and reduce the risk of stroke in patients with conditions like atrial fibrillation.
-
E.
Motrin
Motrin is a widely used over-the-counter ibuprofen pain reliever and fever reducer medication.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Plavix Target entity description: Plavix is a widely used prescription antiplatelet medication (clopidogrel) that helps prevent blood clots and reduce the risk of heart attack and stroke.
-
A.
Brilinta
Brilinta is a prescription antiplatelet medication (ticagrelor) used to reduce the risk of heart attack, stroke, and cardiovascular death in patients with acute coronary syndrome or a history of myocardial infarction.
-
B.
Xarelto
Xarelto is a widely used prescription anticoagulant (blood thinner) that helps prevent and treat blood clots and reduce the risk of stroke in certain patients.
-
C.
Lipitor
Lipitor is a widely prescribed statin medication used to lower cholesterol and reduce the risk of cardiovascular disease.
-
D.
dabigatran
Dabigatran is an oral direct thrombin inhibitor anticoagulant used to prevent and treat blood clots and reduce the risk of stroke in patients with conditions like atrial fibrillation.
-
E.
Motrin
Motrin is a widely used over-the-counter ibuprofen pain reliever and fever reducer medication.
- F. None of above. chosen
Statements (51)
| Predicate | Object |
|---|---|
| instanceOf |
P2Y12 inhibitor
ⓘ
antiplatelet medication ⓘ brand name drug ⓘ pharmaceutical drug ⓘ |
| affects | platelet function ⓘ |
| approvedBy | U.S. Food and Drug Administration NERFINISHED ⓘ |
| coMarketedBy | Bristol-Myers Squibb NERFINISHED ⓘ |
| contraindication |
active pathological bleeding
ⓘ
severe hepatic impairment ⓘ |
| developedBy | Sanofi NERFINISHED ⓘ |
| doesNotAffect | coagulation factors directly ⓘ |
| hasActiveIngredient | clopidogrel bisulfate ⓘ |
| hasATCCode | B01AC04 ⓘ |
| hasBlackBoxWarning | reduced effectiveness in CYP2C19 poor metabolizers ⓘ |
| hasCommonDrugInteraction |
esomeprazole
NERFINISHED
ⓘ
omeprazole ⓘ |
| hasDosageForm | film-coated tablet ⓘ |
| hasDrugClass | thienopyridine ⓘ |
| hasDurationOfEffect | platelet inhibition lasts for platelet lifespan ⓘ |
| hasEffect |
inhibits platelet aggregation
ⓘ
reduces blood clot formation ⓘ |
| hasFDAApprovalYear | 1997 ⓘ |
| hasGenericName | clopidogrel ⓘ |
| hasLegalStatusEU | prescription only ⓘ |
| hasLegalStatusUS | prescription only ⓘ |
| hasMechanismOfAction | irreversible inhibition of platelet P2Y12 ADP receptor ⓘ |
| hasOnsetOfAction | within hours after loading dose ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| hasTypicalStrength |
300 mg tablet
ⓘ
75 mg tablet ⓘ |
| isPrescriptionOnly | true ⓘ |
| isProdrug | true ⓘ |
| majorAdverseEffect |
bleeding
ⓘ
gastrointestinal bleeding ⓘ thrombocytopenia ⓘ |
| metabolizedBy |
CYP2C19
NERFINISHED
ⓘ
CYP3A4 ⓘ |
| oftenUsedWith | aspirin ⓘ |
| pregnancyCategoryUS | B ⓘ |
| rareAdverseEffect | thrombotic thrombocytopenic purpura ⓘ |
| reducesRiskOf |
heart attack
ⓘ
stroke ⓘ vascular death ⓘ |
| requires | hepatic bioactivation ⓘ |
| takenHowOften | once daily ⓘ |
| usedFor |
acute coronary syndrome
ⓘ
management of peripheral arterial disease ⓘ prevention of atherothrombotic events ⓘ prevention of stent thrombosis ⓘ secondary prevention of ischemic stroke ⓘ secondary prevention of myocardial infarction ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Plavix Description of subject: Plavix is a widely used prescription antiplatelet medication (clopidogrel) that helps prevent blood clots and reduce the risk of heart attack and stroke.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.