Axura
E494107
Axura is a brand-name medication containing memantine, commonly prescribed to treat moderate to severe Alzheimer's disease by helping regulate abnormal activity of the neurotransmitter glutamate in the brain.
Statements (40)
| Predicate | Object |
|---|---|
| instanceOf |
brand-name medication
ⓘ
memantine-containing medicine ⓘ |
| actsOn | central nervous system ⓘ |
| affects | glutamatergic neurotransmission ⓘ |
| commonAdverseEffect |
constipation
ⓘ
dizziness ⓘ headache ⓘ hypertension ⓘ somnolence ⓘ |
| contraindication | hypersensitivity to memantine ⓘ |
| drugClass | anti-dementia drug ⓘ |
| elimination | primarily renal ⓘ |
| formulation |
film-coated tablet
ⓘ
oral solution ⓘ |
| hasActiveIngredient | memantine NERFINISHED ⓘ |
| hasDosageForm |
10 mg tablet
ⓘ
20 mg tablet ⓘ |
| hasGenericEquivalent | memantine ⓘ |
| indication |
moderate Alzheimer's disease
ⓘ
severe Alzheimer's disease ⓘ |
| intendedUse | long-term treatment ⓘ |
| mechanismOfAction |
blocks NMDA receptors
ⓘ
reduces pathological effects of excess glutamate ⓘ regulates abnormal glutamatergic neurotransmission ⓘ |
| metabolism | partially hepatic ⓘ |
| onsetOfAction | gradual ⓘ |
| pharmacologicalClass | NMDA receptor antagonist ⓘ |
| pregnancyCategory | use only if clearly needed ⓘ |
| regulates | glutamate activity ⓘ |
| regulatoryStatus | prescription-only medicine ⓘ |
| requiresPrescription | true ⓘ |
| routeOfAdministration | oral ⓘ |
| targetPopulation |
adult patients
ⓘ
elderly patients ⓘ |
| therapeuticArea |
neurology
ⓘ
psychiatry ⓘ |
| treats | Alzheimer's disease NERFINISHED ⓘ |
| usedAs |
adjunct therapy for Alzheimer's disease
ⓘ
monotherapy for Alzheimer's disease ⓘ |
| usedIn | treatment of dementia in Alzheimer's disease ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
Memantine