Namenda
E494105
Namenda is a prescription medication used to treat moderate to severe Alzheimer's disease by regulating the activity of glutamate in the brain.
Statements (47)
| Predicate | Object |
|---|---|
| instanceOf |
brand name medication
ⓘ
pharmaceutical drug ⓘ |
| affects | N-methyl-D-aspartate receptors ⓘ |
| approvalBy | U.S. Food and Drug Administration NERFINISHED ⓘ |
| availableAs |
oral solution
ⓘ
oral tablet ⓘ |
| blackBoxWarning | false ⓘ |
| brandOwnerRegion | United States NERFINISHED ⓘ |
| canBeAdministeredWithFood | true ⓘ |
| chemicalSubClass | adamantane derivative ⓘ |
| commonSideEffect |
confusion
ⓘ
constipation ⓘ dizziness ⓘ headache ⓘ hypertension ⓘ |
| contraindication | known hypersensitivity to memantine ⓘ |
| developedBy |
Allergan
NERFINISHED
ⓘ
Forest Laboratories NERFINISHED ⓘ |
| dosageForm | immediate-release ⓘ |
| eliminationRoute | renal ⓘ |
| FDAApprovalYear | 2003 ⓘ |
| halfLife | about 60–80 hours ⓘ |
| hasActiveIngredient | memantine hydrochloride ⓘ |
| hasATCCode | N06DX01 ⓘ |
| hasExtendedReleaseBrand | Namenda XR NERFINISHED ⓘ |
| hasGenericName | memantine ⓘ |
| indication |
moderate Alzheimer's disease
ⓘ
severe Alzheimer's disease ⓘ |
| isNotDiseaseModifying | true ⓘ |
| legalStatusEU | prescription only ⓘ |
| legalStatusUS | Rx-only ⓘ |
| mayBeUsedWith | cholinesterase inhibitors ⓘ |
| metabolism | minimal hepatic metabolism ⓘ |
| pharmacologicalClass | NMDA receptor antagonist ⓘ |
| pregnancyCategoryUS | Category B ⓘ |
| prescriptionStatus | prescription only ⓘ |
| regulates |
excitatory neurotransmission
ⓘ
glutamate activity in the brain ⓘ |
| requiresCautionIn | severe renal impairment ⓘ |
| routeOfAdministration | oral ⓘ |
| symptomaticTreatment | true ⓘ |
| targetPopulation | patients with moderate to severe Alzheimer's dementia ⓘ |
| therapeuticClass | anti-dementia drug ⓘ |
| treats | Alzheimer's disease NERFINISHED ⓘ |
| usedFor |
cognitive symptoms of Alzheimer's disease
ⓘ
functional symptoms of Alzheimer's disease ⓘ |
| usedIn | adult patients ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
Memantine