Exelon
E494102
Exelon is a brand-name prescription medication containing rivastigmine, used to treat symptoms of mild to moderate dementia associated with Alzheimer's and Parkinson's disease.
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand-name prescription medication
ⓘ
cholinesterase inhibitor ⓘ rivastigmine-containing medicine ⓘ |
| affects | acetylcholine levels in the brain ⓘ |
| belongsToDrugClass |
acetylcholinesterase inhibitors
ⓘ
cholinesterase inhibitors ⓘ |
| commonSideEffect |
diarrhea
ⓘ
dizziness ⓘ loss of appetite ⓘ nausea ⓘ tremor ⓘ vomiting ⓘ weight loss ⓘ |
| contraindication |
known hypersensitivity to rivastigmine
ⓘ
previous severe skin reaction to rivastigmine patch ⓘ |
| dosageForm |
oral capsule
ⓘ
oral solution ⓘ transdermal patch ⓘ |
| effect |
may improve activities of daily living in dementia
ⓘ
may improve or stabilize cognitive function ⓘ |
| hasActiveIngredient | rivastigmine NERFINISHED ⓘ |
| indicatedPopulation |
adults with mild to moderate Alzheimer’s dementia
ⓘ
adults with mild to moderate Parkinson’s disease dementia ⓘ |
| mayCause |
bradycardia
ⓘ
syncope ⓘ |
| mechanismOfAction |
inhibits butyrylcholinesterase
ⓘ
reversibly inhibits acetylcholinesterase ⓘ |
| metabolism | primarily via cholinesterase-mediated hydrolysis ⓘ |
| notIndicatedFor |
severe Alzheimer’s dementia
ⓘ
treatment of behavioral symptoms alone without dementia diagnosis ⓘ |
| regimen | requires gradual dose titration to minimize side effects ⓘ |
| regulatoryStatus | prescription-only medicine ⓘ |
| requires | prescription ⓘ |
| routeOfAdministration |
oral
ⓘ
transdermal ⓘ |
| therapyType | symptomatic treatment of dementia ⓘ |
| treats |
mild dementia associated with Alzheimer’s disease
ⓘ
mild dementia associated with Parkinson’s disease ⓘ moderate dementia associated with Alzheimer’s disease ⓘ moderate dementia associated with Parkinson’s disease ⓘ |
| usedFor |
treatment of cognitive symptoms
ⓘ
treatment of memory impairment ⓘ treatment of reasoning problems ⓘ treatment of thinking problems ⓘ |
| warning |
use with caution in patients with active peptic ulcer disease
ⓘ
use with caution in patients with asthma or obstructive pulmonary disease ⓘ use with caution in patients with cardiac conduction disorders ⓘ use with caution in patients with urinary obstruction ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.