Fentanyl
E490748
Fentanyl is a powerful synthetic opioid analgesic, much stronger than morphine, used medically for severe pain but also widely associated with overdose deaths in the illicit drug market.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Fentanyl canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T5070237 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Fentanyl Context triple: [Money Money 2020, hasPart, Fentanyl]
-
A.
Substiane
Substiane is a La Roche-Posay skincare line formulated to address loss of firmness, density, and comfort in mature or aging skin.
-
B.
Suboxone
Suboxone is a prescription medication combining buprenorphine and naloxone, primarily used to treat opioid dependence by reducing withdrawal symptoms and cravings.
-
C.
Cocaine
Cocaine is a powerful and addictive stimulant drug derived from the coca plant, known for its euphoric effects and significant health and legal risks.
-
D.
Opium
Opium is Playboi Carti’s hip-hop record label and creative collective known for its dark, experimental aesthetic and roster of rising rap artists.
-
E.
Ecstasy
"Ecstasy" is a raw, intense track by PJ Harvey from her critically acclaimed 1993 album *Rid of Me*, showcasing her visceral vocal style and abrasive alternative rock sound.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Fentanyl Target entity description: Fentanyl is a powerful synthetic opioid analgesic, much stronger than morphine, used medically for severe pain but also widely associated with overdose deaths in the illicit drug market.
-
A.
Substiane
Substiane is a La Roche-Posay skincare line formulated to address loss of firmness, density, and comfort in mature or aging skin.
-
B.
Suboxone
Suboxone is a prescription medication combining buprenorphine and naloxone, primarily used to treat opioid dependence by reducing withdrawal symptoms and cravings.
-
C.
Cocaine
Cocaine is a powerful and addictive stimulant drug derived from the coca plant, known for its euphoric effects and significant health and legal risks.
-
D.
Opium
Opium is Playboi Carti’s hip-hop record label and creative collective known for its dark, experimental aesthetic and roster of rising rap artists.
-
E.
Ecstasy
"Ecstasy" is a raw, intense track by PJ Harvey from her critically acclaimed 1993 album *Rid of Me*, showcasing her visceral vocal style and abrasive alternative rock sound.
- F. None of above. chosen
Statements (77)
| Predicate | Object |
|---|---|
| instanceOf |
narcotic analgesic
ⓘ
opioid ⓘ phenylpiperidine ⓘ synthetic opioid analgesic ⓘ |
| actsOnReceptor | mu-opioid receptor NERFINISHED ⓘ |
| antidote | naloxone ⓘ |
| associatedWith |
illicit drug market
ⓘ
opioid overdose epidemic in North America ⓘ |
| ATCCode | N01AH01 ⓘ |
| CASNumber | 437-38-7 ⓘ |
| chemicalFormula | C22H28N2O ⓘ |
| contraindication |
acute severe asthma
ⓘ
significant respiratory depression ⓘ |
| countryOfOrigin | Belgium NERFINISHED ⓘ |
| developedBy |
Janssen Pharmaceutica
NERFINISHED
ⓘ
Paul Janssen NERFINISHED ⓘ |
| durationOfActionIV | 30 to 60 minutes ⓘ |
| excretedBy | kidneys ⓘ |
| halfLife | about 3 to 12 hours depending on formulation ⓘ |
| hasAnalog |
alfentanil
NERFINISHED
ⓘ
carfentanil ⓘ remifentanil NERFINISHED ⓘ sufentanil NERFINISHED ⓘ |
| hasIUPACName | N-phenyl-N-[1-(2-phenylethyl)piperidin-4-yl]propanamide ⓘ |
| illicitForm |
adulterant in counterfeit prescription pills
ⓘ
adulterant in heroin ⓘ counterfeit tablets ⓘ powder ⓘ |
| introducedMedicallyIn | 1960s ⓘ |
| legalStatus |
Schedule II controlled substance in the United States
ⓘ
controlled drug under the Misuse of Drugs Act in the United Kingdom ⓘ controlled substance in Canada ⓘ |
| mechanismOfAction | mu-opioid receptor agonist ⓘ |
| medicalUse |
anesthesia adjunct
ⓘ
management of breakthrough cancer pain ⓘ |
| metabolizedBy | CYP3A4 ⓘ |
| molarMass | 336.47 g/mol ⓘ |
| onsetOfActionIV | within minutes ⓘ |
| overdoseSymptom |
loss of consciousness
ⓘ
pinpoint pupils ⓘ severe respiratory depression ⓘ |
| pharmaceuticalForm |
buccal tablet
ⓘ
injectable solution ⓘ lozenge ⓘ nasal spray ⓘ transdermal patch ⓘ |
| pregnancyCategoryUS | varies by formulation, generally Category C ⓘ |
| primaryMedicalUse | treatment of severe pain ⓘ |
| primaryMetabolite | norfentanyl ⓘ |
| relativePotencyToHeroin | about 30 to 50 times more potent than heroin ⓘ |
| relativePotencyToMorphine | about 50 to 100 times more potent than morphine ⓘ |
| risk |
life-threatening respiratory depression
ⓘ
opioid use disorder ⓘ overdose ⓘ physical dependence ⓘ |
| riskGroup | high risk of fatal overdose in opioid-naive individuals ⓘ |
| routeOfAdministration |
buccal
ⓘ
intramuscular ⓘ intranasal ⓘ intravenous ⓘ sublingual ⓘ transdermal ⓘ |
| sideEffect |
bradycardia
ⓘ
constipation ⓘ nausea ⓘ respiratory depression ⓘ sedation ⓘ |
| solubility | highly lipophilic ⓘ |
| streetName |
Apache
NERFINISHED
ⓘ
China White ⓘ Dance Fever NERFINISHED ⓘ Friend ⓘ Goodfella NERFINISHED ⓘ |
| UNDrugControl | listed in Schedule I of the Single Convention on Narcotic Drugs ⓘ |
| usedIn |
intensive care unit sedation
ⓘ
perioperative anesthesia ⓘ |
| yearOfDiscovery | 1960 ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Fentanyl Description of subject: Fentanyl is a powerful synthetic opioid analgesic, much stronger than morphine, used medically for severe pain but also widely associated with overdose deaths in the illicit drug market.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.