International Prognostic Index

E436083

The International Prognostic Index is a clinical tool that stratifies patients with aggressive non-Hodgkin lymphoma into risk groups based on factors such as age, disease stage, performance status, extranodal involvement, and serum LDH levels to predict outcomes and guide treatment decisions.

All labels observed (1)

Label Occurrences
International Prognostic Index canonical 1

How this entity was disambiguated

Statements (50)

Predicate Object
instanceOf clinical prognostic tool
medical scoring system
oncology prognostic index
risk stratification model
ageCutoffYears 60
appliesTo aggressive non-Hodgkin lymphoma
diffuse large B-cell lymphoma
appliesToPopulation adult patients
basedOnFactor Ann Arbor stage
age
number of extranodal disease sites
performance status
serum lactate dehydrogenase level
commonlyAbbreviatedAs IPI NERFINISHED
developedFor aggressive lymphomas
high-grade lymphomas
intermediate-grade lymphomas
extranodalCriterion more than one extranodal site
field hematologic malignancies
hematology
oncology
hasVariant National Comprehensive Cancer Network IPI NERFINISHED
age-adjusted International Prognostic Index NERFINISHED
revised International Prognostic Index NERFINISHED
influences choice of treatment intensity
consideration of autologous stem cell transplantation in high-risk patients
introducedInDecade 1990s
LDHCriterion elevated serum LDH above normal
limitation less accurate in the rituximab era compared with original development era
measurementType composite clinical score
performanceStatusCriterion ECOG performance status 2 or higher
purpose outcome prediction
prognosis prediction
risk stratification
treatment decision support
riskFactorDefinition Ann Arbor stage III or IV disease
age greater than 60 years
elevated serum LDH
more than one extranodal site of disease
poor performance status
riskGroup high risk
high-intermediate risk
low risk
low-intermediate risk
riskGroupBasis number of adverse prognostic factors
stageCriterion Ann Arbor stage III or IV
usedFor clinical trial stratification
comparisons of treatment outcomes
patient counseling
usesPerformanceScale ECOG performance status

How these facts were elicited

Referenced by (1)

Full triples — surface form annotated when it differs from this entity's canonical label.

non-Hodgkin lymphoma hasPrognosticIndex International Prognostic Index