Calan
E411216
Calan is a brand name for verapamil, a prescription calcium channel blocker medication primarily used to treat high blood pressure, angina, and certain heart rhythm disorders.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Calan canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T4069956 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Calan Context triple: [G. D. Searle & Company, notableProduct, Calan]
-
A.
Tamiathis
Tamiathis is the ancient name of the Egyptian port city now known as Damietta, historically significant for its strategic location on the Nile Delta and the Mediterranean.
-
B.
Alaid
Alaid is a prominent stratovolcano forming the northernmost and highest peak of the Kuril Islands chain between Russia’s Kamchatka Peninsula and Japan.
-
C.
Helidon
Helidon is a small rural town in Queensland, Australia, known for its natural mineral springs and proximity to Toowoomba.
-
D.
Ruabon
Ruabon is a village and community in Wrexham County Borough, Wales, historically known for its coal mining and brickmaking industries and its location on key transport routes.
-
E.
Alba
Alba is the Gaelic name for the early medieval kingdom that evolved into the nation of Scotland.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Calan Target entity description: Calan is a brand name for verapamil, a prescription calcium channel blocker medication primarily used to treat high blood pressure, angina, and certain heart rhythm disorders.
-
A.
Tamiathis
Tamiathis is the ancient name of the Egyptian port city now known as Damietta, historically significant for its strategic location on the Nile Delta and the Mediterranean.
-
B.
Alaid
Alaid is a prominent stratovolcano forming the northernmost and highest peak of the Kuril Islands chain between Russia’s Kamchatka Peninsula and Japan.
-
C.
Helidon
Helidon is a small rural town in Queensland, Australia, known for its natural mineral springs and proximity to Toowoomba.
-
D.
Ruabon
Ruabon is a village and community in Wrexham County Borough, Wales, historically known for its coal mining and brickmaking industries and its location on key transport routes.
-
E.
Alba
Alba is the Gaelic name for the early medieval kingdom that evolved into the nation of Scotland.
- F. None of above. chosen
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
brand name drug
ⓘ
pharmaceutical product ⓘ |
| belongsToRegulatoryCategory | cardiovascular medication ⓘ |
| contraindicatedIn |
cardiogenic shock
ⓘ
second‑degree atrioventricular block without pacemaker ⓘ severe hypotension ⓘ sick sinus syndrome without pacemaker ⓘ third‑degree atrioventricular block without pacemaker ⓘ |
| hasActiveIngredient | verapamil ⓘ |
| hasAdministrationFrequency | multiple times daily (immediate‑release) ⓘ |
| hasDosageForm |
extended‑release tablet
ⓘ
tablet ⓘ |
| hasDrugClass | calcium channel blocker ⓘ |
| hasDrugSubclass | non‑dihydropyridine calcium channel blocker ⓘ |
| hasEffect |
decreases myocardial contractility
ⓘ
dilates coronary arteries ⓘ lowers blood pressure ⓘ reduces systemic vascular resistance ⓘ slows atrioventricular nodal conduction ⓘ |
| hasGenericName | verapamil ⓘ |
| hasMechanismOfAction |
blocks L‑type calcium channels
ⓘ
reduces calcium influx into cardiac muscle cells ⓘ reduces calcium influx into vascular smooth muscle cells ⓘ |
| hasPregnancyCategory | use only if clearly needed ⓘ |
| hasRouteOfAdministration | oral ⓘ |
| interactsWith |
CYP3A4 inducers
ⓘ
CYP3A4 inhibitors ⓘ beta blockers ⓘ digoxin ⓘ |
| mayCauseAdverseEffect |
bradycardia
ⓘ
constipation ⓘ dizziness ⓘ edema ⓘ headache ⓘ hypotension ⓘ |
| regulatedAs | prescription‑only medicine ⓘ |
| requires | prescription ⓘ |
| treatsSystem | cardiovascular system ⓘ |
| usedFor |
Prinzmetal angina
ⓘ
angina pectoris ⓘ atrial fibrillation with rapid ventricular response ⓘ atrial flutter with rapid ventricular response ⓘ chronic stable angina ⓘ high blood pressure ⓘ hypertension ⓘ paroxysmal supraventricular tachycardia ⓘ supraventricular tachycardia ⓘ vasospastic angina ⓘ |
How these facts were elicited
The pipeline generated the facts above by prompting gpt-5.1 with this entity's name + description and the instruction below.
Instruction
You are a knowledge base construction expert. Given a subject entity and a description of it, return factual statements that you know for the subject as a JSON list of dictionaries(triples), where keys must be "subject", "predicate" and "object". The number of facts may be very high, between 25 to 50 or more, for very popular subjects. For less popular subjects, the number of facts can be very low, like 5 or 10. # Requirements - If you don't know the subject at all, return an empty list. - If the subject is not a named entity, return an empty list. - Include at least one triple where predicate is "instanceOf". - Do not get too wordy. - Separate several objects into multiple triples with one object.
Input
Subject: Calan Description of subject: Calan is a brand name for verapamil, a prescription calcium channel blocker medication primarily used to treat high blood pressure, angina, and certain heart rhythm disorders.
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.