Veklury
E409698
Veklury is the brand name for remdesivir, an antiviral medication used primarily to treat COVID-19.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Veklury canonical | 1 |
Statements (48)
| Predicate | Object |
|---|---|
| instanceOf |
antiviral medication
ⓘ
brand name drug ⓘ |
| administrationSetting |
hospital
ⓘ
outpatient infusion center ⓘ |
| adverseEffect |
hypersensitivity reactions
ⓘ
nausea ⓘ transaminase elevations ⓘ |
| ageGroupIndicated |
adults
ⓘ
pediatric patients ⓘ |
| approvalYear | 2020 ⓘ |
| ATCCode | J05AB16 ⓘ |
| belongsTo | COVID-19 therapeutics ⓘ |
| chemicalSubstance | GS-5734 ⓘ |
| contraindication | severe hypersensitivity to remdesivir ⓘ |
| countryApprovedIn |
European Union
ⓘ
United States of America ⓘ
surface form:
United States
|
| developedBy |
Gilead Sciences (board member)
ⓘ
surface form:
Gilead Sciences
|
| dosageForm | 100 mg vial ⓘ |
| formulation |
intravenous solution
ⓘ
lyophilized powder for injection ⓘ |
| hasActiveIngredient | remdesivir ⓘ |
| hasPatentHolder |
Gilead Sciences (board member)
ⓘ
surface form:
Gilead Sciences
|
| indication |
treatment of hospitalized COVID-19 patients
ⓘ
treatment of non-hospitalized COVID-19 patients at high risk of progression ⓘ |
| initialAuthorizationType | Emergency Use Authorization ⓘ |
| isProdrugOf | GS-441524 triphosphate ⓘ |
| laterAuthorizationType | full approval ⓘ |
| manufacturer |
Gilead Sciences (board member)
ⓘ
surface form:
Gilead Sciences
|
| mechanismOfAction | RNA-dependent RNA polymerase inhibitor ⓘ |
| monitoringRequirement |
liver function tests
ⓘ
renal function tests ⓘ |
| pharmacologicalClass |
antiviral
ⓘ
nucleotide analog ⓘ |
| pregnancyCategory | use only if potential benefit justifies potential risk ⓘ |
| regimenCharacteristic | fixed-duration course ⓘ |
| regulatoryStatus |
EMA approved
ⓘ
FDA approved ⓘ |
| requires | intravenous access ⓘ |
| routeOfAdministration | intravenous infusion ⓘ |
| targets | SARS-CoV-2 RNA-dependent RNA polymerase ⓘ |
| therapyArea |
infectious diseases
ⓘ
virology ⓘ |
| tradeNameOf | remdesivir ⓘ |
| usedDuring | COVID-19 pandemic ⓘ |
| usedFor |
COVID-19 pandemic
ⓘ
surface form:
COVID-19
SARS-CoV-2 infection ⓘ |
| warning |
may cause elevated liver enzymes
ⓘ
use with caution in patients with renal impairment ⓘ |
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.
subject surface form:
Gilead Sciences