Isabella of Portugal, Holy Roman Empress

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Isabella of Portugal, Holy Roman Empress, was a 16th-century Portuguese infanta who became Holy Roman Empress and Queen of Spain as the wife of Emperor Charles V and played a key political role as his regent.

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Full triples — surface form annotated when it differs from this entity's canonical label.

King John III of Portugal → sibling → Isabella of Portugal, Holy Roman Empress ⓘ

subject surface form: John III of Portugal