ABO blood group system
E174349
The ABO blood group system is the primary human blood classification method based on the presence or absence of specific antigens on red blood cells, crucial for safe blood transfusions and organ transplantation.
All labels observed (3)
| Label | Occurrences |
|---|---|
| ABO blood group system canonical | 1 |
| ABO gene | 1 |
| H antigen | 1 |
Statements (50)
| Predicate | Object |
|---|---|
| instanceOf |
blood group system
ⓘ
human blood classification system ⓘ |
| ABTypeCharacteristic | presence of both A and B antigens ⓘ |
| antibodyClass | mainly IgM in plasma ⓘ |
| antigenBiochemicalNature | carbohydrate structure ⓘ |
| antigenPrecursor | H substance ⓘ |
| antigensExpressedOn |
endothelial cells
ⓘ
epithelial cells ⓘ platelets ⓘ red blood cells ⓘ secretions (in secretors) ⓘ |
| ATypeCharacteristic | presence of A antigen ⓘ |
| basedOnAntibody |
anti-A antibody
ⓘ
anti-B antibody ⓘ |
| basedOnAntigen |
A antigen
ⓘ
B antigen ⓘ ABO blood group system self-linksurface differs ⓘ
surface form:
H antigen
|
| BTypeCharacteristic | presence of B antigen ⓘ |
| chromosomalLocation | chromosome 9q34 ⓘ |
| clinicalSignificance |
hemolytic disease of the fetus and newborn (less common than Rh)
ⓘ
hemolytic transfusion reactions ⓘ organ transplant rejection risk ⓘ |
| determines | ABO blood type ⓘ |
| discoveredBy | Karl Landsteiner ⓘ |
| discoveryYear | 1900 ⓘ |
| hasAllele |
IA
ⓘ
IB ⓘ i ⓘ |
| hasBloodGroup |
A
ⓘ
AB ⓘ B ⓘ O ⓘ |
| hasGeneticLocus |
ABO blood group system
self-linksurface differs
ⓘ
surface form:
ABO gene
|
| hasPhenotypeFrequencyVariation | varies by population and ethnicity ⓘ |
| hasSubgroup |
A1
ⓘ
A2 ⓘ |
| hasUniversalDonorType | O negative (for red cells, considering Rh system) ⓘ |
| hasUniversalRecipientType | AB positive (for red cells, considering Rh system) ⓘ |
| inheritancePattern | autosomal codominant ⓘ |
| ISBTNumber | 001 ⓘ |
| namedAfter | A and B antigens ⓘ |
| OTypeCharacteristic | absence of A and B antigens ⓘ |
| partOf | human immunohematology ⓘ |
| relatedTo | Rh blood group system ⓘ |
| standardizedBy | International Society of Blood Transfusion ⓘ |
| testingMethod |
forward typing (cell grouping)
ⓘ
reverse typing (serum grouping) ⓘ |
| usedFor |
blood transfusion compatibility
ⓘ
organ transplantation compatibility ⓘ tissue typing ⓘ |
Referenced by (3)
Full triples — surface form annotated when it differs from this entity's canonical label.
this entity surface form:
H antigen
this entity surface form:
ABO gene