COX-2
E1243367
UNEXPLORED
COX-2 is an inducible cyclooxygenase enzyme involved in inflammation and pain by catalyzing the formation of prostaglandins from arachidonic acid.
All labels observed (1)
| Label | Occurrences |
|---|---|
| COX-2 canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T16952507 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: COX-2 Context triple: [Daypro, inhibits, COX-2]
-
A.
Celebrex
Celebrex is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in conditions such as arthritis.
-
B.
tumor necrosis factor alpha
Tumor necrosis factor alpha is a pro-inflammatory cytokine involved in immune regulation and inflammation, playing a key role in autoimmune and inflammatory diseases.
-
C.
TNF
TNF is a weekly National Football League (NFL) primetime broadcast package featuring games played on Thursday nights during the regular season.
-
D.
IL-17A
IL-17A is a pro-inflammatory cytokine produced mainly by Th17 cells that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases.
-
E.
Activase
Activase is a brand-name form of the clot-dissolving drug alteplase, widely used as a thrombolytic treatment for acute ischemic stroke and certain types of heart attack and pulmonary embolism.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: COX-2 Target entity description: COX-2 is an inducible cyclooxygenase enzyme involved in inflammation and pain by catalyzing the formation of prostaglandins from arachidonic acid.
-
A.
Celebrex
Celebrex is a prescription nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain and inflammation in conditions such as arthritis.
-
B.
tumor necrosis factor alpha
Tumor necrosis factor alpha is a pro-inflammatory cytokine involved in immune regulation and inflammation, playing a key role in autoimmune and inflammatory diseases.
-
C.
TNF
TNF is a weekly National Football League (NFL) primetime broadcast package featuring games played on Thursday nights during the regular season.
-
D.
IL-17A
IL-17A is a pro-inflammatory cytokine produced mainly by Th17 cells that plays a key role in the pathogenesis of several autoimmune and inflammatory diseases.
-
E.
Activase
Activase is a brand-name form of the clot-dissolving drug alteplase, widely used as a thrombolytic treatment for acute ischemic stroke and certain types of heart attack and pulmonary embolism.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.