Preiss–Handler pathway
E1159680
UNEXPLORED
The Preiss–Handler pathway is a metabolic route in which cells convert nicotinic acid (niacin) into NAD+, a vital coenzyme involved in redox reactions and energy metabolism.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Preiss–Handler pathway canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T15478608 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Preiss–Handler pathway Context triple: [NAD+, isBiosynthesizedVia, Preiss–Handler pathway]
-
A.
Leloir pathway of galactose metabolism
The Leloir pathway of galactose metabolism is the primary biochemical route by which cells convert galactose into glucose-1-phosphate for entry into central energy and biosynthetic pathways.
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B.
Calvin cycle
The Calvin cycle is the series of biochemical reactions in photosynthetic organisms that use carbon dioxide and energy-rich molecules (ATP and NADPH) to synthesize organic sugars.
-
C.
Warburg effect
The Warburg effect is a phenomenon in which cancer cells preferentially produce energy through high-rate glycolysis followed by lactic acid fermentation, even in the presence of sufficient oxygen.
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D.
Sharpless aminohydroxylation
Sharpless aminohydroxylation is a stereoselective chemical reaction that converts alkenes into vicinal amino alcohols using a chiral catalyst, widely used in asymmetric synthesis.
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E.
DAGL enzyme
The DAGL enzyme is a key biosynthetic enzyme in the endocannabinoid system that produces the signaling lipid 2-arachidonoylglycerol (2-AG) from diacylglycerol.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Preiss–Handler pathway Target entity description: The Preiss–Handler pathway is a metabolic route in which cells convert nicotinic acid (niacin) into NAD+, a vital coenzyme involved in redox reactions and energy metabolism.
-
A.
Leloir pathway of galactose metabolism
The Leloir pathway of galactose metabolism is the primary biochemical route by which cells convert galactose into glucose-1-phosphate for entry into central energy and biosynthetic pathways.
-
B.
Calvin cycle
The Calvin cycle is the series of biochemical reactions in photosynthetic organisms that use carbon dioxide and energy-rich molecules (ATP and NADPH) to synthesize organic sugars.
-
C.
Warburg effect
The Warburg effect is a phenomenon in which cancer cells preferentially produce energy through high-rate glycolysis followed by lactic acid fermentation, even in the presence of sufficient oxygen.
-
D.
Sharpless aminohydroxylation
Sharpless aminohydroxylation is a stereoselective chemical reaction that converts alkenes into vicinal amino alcohols using a chiral catalyst, widely used in asymmetric synthesis.
-
E.
DAGL enzyme
The DAGL enzyme is a key biosynthetic enzyme in the endocannabinoid system that produces the signaling lipid 2-arachidonoylglycerol (2-AG) from diacylglycerol.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.