Warburg effect
E1135977
UNEXPLORED
The Warburg effect is a phenomenon in which cancer cells preferentially produce energy through high-rate glycolysis followed by lactic acid fermentation, even in the presence of sufficient oxygen.
All labels observed (1)
| Label | Occurrences |
|---|---|
| Warburg effect canonical | 1 |
How this entity was disambiguated
This entity first appeared as the object of triple T15075185 — resolving that mention is where its identity was fixed. The disambiguator weighed these candidate entities and picked the highlighted one (or “None”, minting a new entity). This is how homonymy is resolved: the same surface form can point to different entities.
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Warburg effect Context triple: [Otto Warburg, notableConcept, Warburg effect]
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A.
PI3K-AKT signaling pathway
The PI3K-AKT signaling pathway is a key intracellular cascade that regulates cell growth, survival, metabolism, and proliferation, and is frequently dysregulated in cancer.
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B.
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases
The Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases is a research consortium focused on understanding how cellular stress mechanisms contribute to aging and age-related diseases to develop new therapeutic strategies.
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C.
The Death of Cancer
The Death of Cancer is a nonfiction book by oncologist Vincent T. DeVita Jr. that chronicles the history, politics, and evolving science of cancer treatment from an insider’s perspective.
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D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
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E.
Leloir pathway of galactose metabolism
The Leloir pathway of galactose metabolism is the primary biochemical route by which cells convert galactose into glucose-1-phosphate for entry into central energy and biosynthetic pathways.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: Warburg effect Target entity description: The Warburg effect is a phenomenon in which cancer cells preferentially produce energy through high-rate glycolysis followed by lactic acid fermentation, even in the presence of sufficient oxygen.
-
A.
PI3K-AKT signaling pathway
The PI3K-AKT signaling pathway is a key intracellular cascade that regulates cell growth, survival, metabolism, and proliferation, and is frequently dysregulated in cancer.
-
B.
Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases
The Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases is a research consortium focused on understanding how cellular stress mechanisms contribute to aging and age-related diseases to develop new therapeutic strategies.
-
C.
The Death of Cancer
The Death of Cancer is a nonfiction book by oncologist Vincent T. DeVita Jr. that chronicles the history, politics, and evolving science of cancer treatment from an insider’s perspective.
-
D.
c-Myc
c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
-
E.
Leloir pathway of galactose metabolism
The Leloir pathway of galactose metabolism is the primary biochemical route by which cells convert galactose into glucose-1-phosphate for entry into central energy and biosynthetic pathways.
- F. None of above. chosen
Referenced by (1)
Full triples — surface form annotated when it differs from this entity's canonical label.