Triple

T5981453
Position Surface form Disambiguated ID Type / Status
Subject Donepezil E133125 entity
Predicate metabolizedBy P37221 FINISHED
Object CYP3A4 E242412 NE FINISHED

Named-entity recognition

Before disambiguation, gpt-5-mini classified whether the object phrase is a named entity — the step behind the object's NE type shown above.

Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: CYP3A4 | Statement: [Donepezil, metabolizedBy, CYP3A4]

Disambiguation candidates (1 decision)

The exact options the model was shown at each disambiguation step, with the option it chose highlighted — the evidence behind this triple's disambiguated ids.

NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: CYP3A4
Context triple: [Donepezil, metabolizedBy, CYP3A4]
  • A. CYP3A4 chosen
    CYP3A4 is a major human liver and intestinal enzyme of the cytochrome P450 family responsible for metabolizing a wide range of drugs and xenobiotics.
  • B. CYP2J2
    CYP2J2 is a human cytochrome P450 enzyme primarily expressed in the heart and other tissues, involved in the metabolism of various drugs and endogenous fatty acids.
  • C. P-glycoprotein
    P-glycoprotein is a membrane-bound efflux transporter protein that pumps various drugs and xenobiotics out of cells, influencing their absorption, distribution, and resistance profiles.
  • D. BCRP
    BCRP is the Central Reserve Bank of Peru, the country’s monetary authority responsible for maintaining monetary stability and managing its currency and international reserves.
  • E. BCRP
    BCRP (Breast Cancer Resistance Protein) is an ATP-binding cassette (ABC) efflux transporter involved in multidrug resistance and the transport of various drugs and xenobiotics across cellular membranes.
  • F. None of above.
  • G. Unsure - the case is ambiguous/there is not enough information to decide.

Provenance (3 batches)

Stage Batch ID Job type Status
creating batch_69c0086f45e8819098f73dd16d45ec9d elicitation completed
NER batch_69c0560bae148190ad4755defaaf471b ner completed
NED1 batch_69c0e42174a88190b8b40cbc7815911f ned_source_triple completed
Created at: March 22, 2026, 4:04 p.m.