Triple
T33291931
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Mitoxantrone |
E852340
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | topoisomerase II inhibitor |
C59771
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: topoisomerase II inhibitor Context triple: [Mitoxantrone, instanceOf, topoisomerase II inhibitor]
-
A.
topoisomerase I inhibitor
A topoisomerase I inhibitor is a drug that blocks the activity of the topoisomerase I enzyme, preventing DNA strand relaxation during replication and transcription and thereby inducing DNA damage and cell death, particularly in rapidly dividing cells.
-
B.
PARP inhibitor
A PARP inhibitor is a targeted anticancer drug that blocks poly(ADP-ribose) polymerase enzymes to prevent DNA repair in tumor cells, leading to their death, particularly in cancers with existing DNA repair defects such as BRCA-mutated tumors.
-
C.
mitotic inhibitor
A mitotic inhibitor is a substance that disrupts or halts cell division by interfering with the processes of mitosis, often used in cancer therapy to prevent rapidly dividing tumor cells from proliferating.
-
D.
CDK4/6 inhibitor
A CDK4/6 inhibitor is a targeted anticancer drug that blocks cyclin-dependent kinases 4 and 6 to halt cell cycle progression from G1 to S phase, thereby inhibiting tumor cell proliferation.
-
E.
alkylating agent
An alkylating agent is a chemical compound that transfers alkyl groups to biological molecules, often DNA, leading to disruption of normal cellular function and frequently used in chemotherapy to kill rapidly dividing cells.
- F. None of above. chosen
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69f349660ff48190a4568803d0b89941 |
completed | April 30, 2026, 12:21 p.m. |
Created at: May 1, 2026, 1:32 a.m.