Triple

T2370975
Position Surface form Disambiguated ID Type / Status
Subject Herceptin E46088 entity
Predicate antibodyTarget P37229 FINISHED
Object ERBB2
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
E261825 NE FINISHED

How this triple was built (5 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: ERBB2 | Statement: [Herceptin, antibodyTarget, ERBB2]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: ERBB2
Context triple: [Herceptin, antibodyTarget, ERBB2]
  • A. EGF
    EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
  • B. CD38
    CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
  • C. TARDBP
    TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
  • D. AACR2
    AACR2 (Anglo-American Cataloguing Rules, Second Edition) is a widely used library cataloging standard that provides rules for describing and accessing library materials in online and card catalogs.
  • E. Herceptin
    Herceptin is a targeted monoclonal antibody drug used primarily to treat HER2-positive breast cancer by blocking the HER2 receptor on cancer cells.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: ERBB2
Triple: [Herceptin, antibodyTarget, ERBB2]
Generated description
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: ERBB2
Target entity description: ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
  • A. EGF
    EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
  • B. ERK
    ERK is the abbreviation for the Evangelical Reformed Church, a Protestant regional church within the Reformed tradition.
  • C. CD38
    CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
  • D. TARDBP
    TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
  • E. AACR2
    AACR2 (Anglo-American Cataloguing Rules, Second Edition) is a widely used library cataloging standard that provides rules for describing and accessing library materials in online and card catalogs.
  • F. None of above. chosen
PD Predicate disambiguation gpt-5-mini-2025-08-07
Target predicate: antibodyTarget
Context triple: [Herceptin, antibodyTarget, ERBB2]
  • A. antibodyType
    Indicates the specific class or subtype of an antibody involved in the described relationship or context.
  • B. antigen chosen
    Indicates that one entity functions as an antigen in relation to another, typically provoking or being recognized by an immune response.
  • C. hasMolecularTarget
    Indicates that one entity (such as a drug or compound) is directed toward, binds to, or specifically interacts with a particular molecular target (such as a protein, receptor, or gene).
  • D. hasTargetDisease
    Indicates that an entity (such as a treatment, study, or intervention) is directed toward, intended to affect, or primarily concerned with a specified disease.
  • E. hasProteinBinding
    Indicates that one entity is capable of physically binding to or interacting specifically with a protein.
  • F. None of above.

Provenance (6 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69a88a145268819083e2736cb835c696 completed March 4, 2026, 7:37 p.m.
NER Named-entity recognition batch_69abc76f5aec8190867d621e6849258c completed March 7, 2026, 6:36 a.m.
NED1 Entity disambiguation (via context triple) batch_69aea8a2b1448190b19179cf379993ee completed March 9, 2026, 11:01 a.m.
NEDg Description generation batch_69aeac6b13ac81909042dddef15ec924 completed March 9, 2026, 11:18 a.m.
NED2 Entity disambiguation (via description) batch_69aead16b0a881909103e26053cfad84 completed March 9, 2026, 11:20 a.m.
PD Predicate disambiguation batch_69abc59b88348190a2d6c08f69974117 completed March 7, 2026, 6:28 a.m.
Created at: March 4, 2026, 7:56 p.m.