Triple
T2370975
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | Herceptin |
E46088
|
entity |
| Predicate | antibodyTarget |
P37229
|
FINISHED |
| Object |
ERBB2
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
|
E261825
|
NE FINISHED |
How this triple was built (5 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: ERBB2 | Statement: [Herceptin, antibodyTarget, ERBB2]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: ERBB2 Context triple: [Herceptin, antibodyTarget, ERBB2]
-
A.
EGF
EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
-
B.
CD38
CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
-
C.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
D.
AACR2
AACR2 (Anglo-American Cataloguing Rules, Second Edition) is a widely used library cataloging standard that provides rules for describing and accessing library materials in online and card catalogs.
-
E.
Herceptin
Herceptin is a targeted monoclonal antibody drug used primarily to treat HER2-positive breast cancer by blocking the HER2 receptor on cancer cells.
- F. None of above. chosen
- G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg
Description generation
gpt-5.1
Instruction
Generate a one-sentence description of the target entity. You are given a context triple in the form (subject, predicate, object), where the object is the target entity. # Instructions Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. Avoid repeating the information from the triple, unless really essential. # Response Format Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: ERBB2 Triple: [Herceptin, antibodyTarget, ERBB2]
Generated description
ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
NED2
Entity disambiguation (via description)
gpt-5-mini-2025-08-07
Target entity: ERBB2 Target entity description: ERBB2, also known as HER2, is a receptor tyrosine kinase frequently overexpressed in certain breast and other cancers and serves as a key therapeutic target.
-
A.
EGF
EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
-
B.
ERK
ERK is the abbreviation for the Evangelical Reformed Church, a Protestant regional church within the Reformed tradition.
-
C.
CD38
CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
-
D.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
-
E.
AACR2
AACR2 (Anglo-American Cataloguing Rules, Second Edition) is a widely used library cataloging standard that provides rules for describing and accessing library materials in online and card catalogs.
- F. None of above. chosen
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: antibodyTarget Context triple: [Herceptin, antibodyTarget, ERBB2]
-
A.
antibodyType
Indicates the specific class or subtype of an antibody involved in the described relationship or context.
-
B.
antigen
chosen
Indicates that one entity functions as an antigen in relation to another, typically provoking or being recognized by an immune response.
-
C.
hasMolecularTarget
Indicates that one entity (such as a drug or compound) is directed toward, binds to, or specifically interacts with a particular molecular target (such as a protein, receptor, or gene).
-
D.
hasTargetDisease
Indicates that an entity (such as a treatment, study, or intervention) is directed toward, intended to affect, or primarily concerned with a specified disease.
-
E.
hasProteinBinding
Indicates that one entity is capable of physically binding to or interacting specifically with a protein.
- F. None of above.
Provenance (6 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69a88a145268819083e2736cb835c696 |
completed | March 4, 2026, 7:37 p.m. |
| NER | Named-entity recognition | batch_69abc76f5aec8190867d621e6849258c |
completed | March 7, 2026, 6:36 a.m. |
| NED1 | Entity disambiguation (via context triple) | batch_69aea8a2b1448190b19179cf379993ee |
completed | March 9, 2026, 11:01 a.m. |
| NEDg | Description generation | batch_69aeac6b13ac81909042dddef15ec924 |
completed | March 9, 2026, 11:18 a.m. |
| NED2 | Entity disambiguation (via description) | batch_69aead16b0a881909103e26053cfad84 |
completed | March 9, 2026, 11:20 a.m. |
| PD | Predicate disambiguation | batch_69abc59b88348190a2d6c08f69974117 |
completed | March 7, 2026, 6:28 a.m. |
Created at: March 4, 2026, 7:56 p.m.