Triple

T2370957
Position Surface form Disambiguated ID Type / Status
Subject Herceptin E46088 entity
Predicate targets P860 FINISHED
Object HER2 receptor
The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
E261824 NE FINISHED

How this triple was built (4 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: HER2 receptor | Statement: [Herceptin, targets, HER2 receptor]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: HER2 receptor
Context triple: [Herceptin, targets, HER2 receptor]
  • A. Herceptin
    Herceptin is a targeted monoclonal antibody drug used primarily to treat HER2-positive breast cancer by blocking the HER2 receptor on cancer cells.
  • B. EGF
    EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
  • C. P-glycoprotein
    P-glycoprotein is a membrane-bound efflux transporter protein that pumps various drugs and xenobiotics out of cells, influencing their absorption, distribution, and resistance profiles.
  • D. programmed death-ligand 1
    Programmed death-ligand 1 (PD-L1) is an immune checkpoint protein expressed on various cells that suppresses T-cell activity by engaging PD-1, enabling tumors to evade immune surveillance.
  • E. CD38
    CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NEDg Description generation gpt-5.1
Instruction
Generate a one-sentence description of the target entity. 
You are given a context triple in the form (subject, predicate, object), where the object is the target entity. 
# Instructions
Use the triple to infer relevant information about the entity. Describe the entity based on what is most defining, well-known. 
Avoid repeating the information from the triple, unless really essential.
# Response Format
Return only the sentence: "Description: [one-sentence description of the target entity]"
Input
Entity: HER2 receptor
Triple: [Herceptin, targets, HER2 receptor]
Generated description
The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: HER2 receptor
Target entity description: The HER2 receptor is a cell surface protein and member of the epidermal growth factor receptor family that, when overexpressed, drives the growth of certain aggressive breast and other cancers.
  • A. Herceptin
    Herceptin is a targeted monoclonal antibody drug used primarily to treat HER2-positive breast cancer by blocking the HER2 receptor on cancer cells.
  • B. EGF
    EGF is the ICAO airline designator used to identify American Eagle Airlines in aviation operations and communications.
  • C. P-glycoprotein
    P-glycoprotein is a membrane-bound efflux transporter protein that pumps various drugs and xenobiotics out of cells, influencing their absorption, distribution, and resistance profiles.
  • D. programmed death-ligand 1
    Programmed death-ligand 1 (PD-L1) is an immune checkpoint protein expressed on various cells that suppresses T-cell activity by engaging PD-1, enabling tumors to evade immune surveillance.
  • E. CD38
    CD38 is a cell surface glycoprotein with ectoenzyme and receptor functions, highly expressed on plasma cells and targeted in therapies for multiple myeloma and other hematologic malignancies.
  • F. None of above. chosen

Provenance (5 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69a88a145268819083e2736cb835c696 completed March 4, 2026, 7:37 p.m.
NER Named-entity recognition batch_69abc76f5aec8190867d621e6849258c completed March 7, 2026, 6:36 a.m.
NED1 Entity disambiguation (via context triple) batch_69aea8a2b1448190b19179cf379993ee completed March 9, 2026, 11:01 a.m.
NEDg Description generation batch_69aeac6b13ac81909042dddef15ec924 completed March 9, 2026, 11:18 a.m.
NED2 Entity disambiguation (via description) batch_69aead16b0a881909103e26053cfad84 completed March 9, 2026, 11:20 a.m.
Created at: March 4, 2026, 7:56 p.m.