Triple
T22863027
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | LOXO-305 |
E566975
|
entity |
| Predicate | hasTarget |
P14889
|
FINISHED |
| Object | Bruton’s tyrosine kinase |
—
|
NE NERFINISHED |
How this triple was built (2 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: Bruton’s tyrosine kinase | Statement: [LOXO-305, hasTarget, Bruton’s tyrosine kinase]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: Bruton’s tyrosine kinase Context triple: [LOXO-305, hasTarget, Bruton’s tyrosine kinase]
-
A.
Bruton tyrosine kinase
Bruton tyrosine kinase is a key signaling enzyme in B cells that plays a crucial role in their development and function and is a major therapeutic target in certain blood cancers and autoimmune diseases.
-
B.
Janus kinase 1
Janus kinase 1 is a tyrosine kinase enzyme involved in cytokine receptor signaling and immune regulation, making it an important therapeutic target in inflammatory and autoimmune diseases.
-
C.
BTK
BTK is the ICAO airline designator assigned to Batik Air, an Indonesian full-service carrier.
-
D.
BTK
chosen
BTK (Bruton’s tyrosine kinase) is a key signaling enzyme in B cells and a major therapeutic target in certain blood cancers and autoimmune diseases.
-
E.
CD22
CD22 is a B-cell–specific surface glycoprotein that functions as an inhibitory co-receptor modulating B cell receptor signaling and immune responses.
- F. None of above.
- G. Unsure - the case is ambiguous/there is not enough information to decide.
Provenance (2 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e24589083081908d5694c4fdc80086 |
completed | April 17, 2026, 2:36 p.m. |
| NER | Named-entity recognition | batch_69f17efdc3b08190be03d856aa86b277 |
completed | April 29, 2026, 3:46 a.m. |
Created at: April 17, 2026, 3:38 p.m.