Triple
T22693096
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | SMCR8 |
E561100
|
entity |
| Predicate | geneticInteractionWith |
P149319
|
FINISHED |
| Object | C9orf72 |
—
|
NE NERFINISHED |
How this triple was built (3 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: C9orf72 | Statement: [SMCR8, geneticInteractionWith, C9orf72]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: C9orf72 Context triple: [SMCR8, geneticInteractionWith, C9orf72]
-
A.
C9orf72
chosen
C9orf72 is a human gene whose hexanucleotide repeat expansions are the most common known genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD).
-
B.
SMN2
SMN2 is a human gene that produces a backup form of survival motor neuron protein and is a key therapeutic target in spinal muscular atrophy.
-
C.
SOD1
SOD1 is a gene encoding the antioxidant enzyme superoxide dismutase 1, whose mutations are a major known cause of familial amyotrophic lateral sclerosis (ALS).
-
D.
Cln3
Cln3 is a G1 cyclin in budding yeast that helps trigger the Start transition of the cell cycle by activating the Cdc28 cyclin-dependent kinase.
-
E.
TARDBP
TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
- F. None of above.
- G. Unsure - the case is ambiguous/there is not enough information to decide.
PD
Predicate disambiguation
gpt-5-mini-2025-08-07
Target predicate: geneticInteractionWith Context triple: [SMCR8, geneticInteractionWith, C9orf72]
-
A.
regulatoryInteraction
Indicates a relationship where one entity modulates, controls, or influences the activity, expression, or function of another entity through regulatory mechanisms.
-
B.
geneticallyLinkedTo
Indicates a relationship where two entities share a genetic connection, such as common ancestry, shared genes, or hereditary association.
-
C.
associatedWithPhenotype
Indicates that an entity has a documented connection or correlation with a particular phenotype or observable trait.
-
D.
geneticExchange
Indicates the transfer or sharing of genetic material between entities, resulting in altered or recombined genetic information.
-
E.
geneticAffinity
Indicates a relationship where entities share a notable degree of genetic similarity or relatedness.
- F. None of above. chosen
Provenance (4 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454d71b48190a1f80af9f82b6fcf |
completed | April 17, 2026, 2:35 p.m. |
| NER | Named-entity recognition | batch_69f1789c6ae481908975b7d27e7624ac |
completed | April 29, 2026, 3:18 a.m. |
| PD | Predicate disambiguation | batch_69ee62b2259c819091ed1387a748b9f3 |
completed | April 26, 2026, 7:08 p.m. |
| PDg | Predicate description generation | batch_69ee8843d3308190b6e22bb98ae5c3d8 |
completed | April 26, 2026, 9:48 p.m. |
Created at: April 17, 2026, 3:13 p.m.