Triple
T22690521
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | LOXO-292 |
E561037
|
entity |
| Predicate | targets |
P860
|
FINISHED |
| Object | RET kinase |
—
|
NE NERFINISHED |
How this triple was built (2 steps)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
NER
Named-entity recognition
gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: RET kinase | Statement: [LOXO-292, targets, RET kinase]
NED1
Entity disambiguation (via context triple)
gpt-5-mini-2025-08-07
Target entity: RET kinase Context triple: [LOXO-292, targets, RET kinase]
-
A.
RET kinase
chosen
RET kinase is a receptor tyrosine kinase involved in cell growth and differentiation whose activating alterations drive several cancers, making it an important therapeutic target.
-
B.
ERK
ERK is the abbreviation for the Evangelical Reformed Church, a Protestant regional church within the Reformed tradition.
-
C.
CDK6
CDK6 is a cyclin-dependent kinase that regulates cell cycle progression and is a key target in certain cancer therapies.
-
D.
CDK7 kinase
CDK7 kinase is a cyclin-dependent kinase that functions as a key regulator of transcription initiation and cell cycle control by phosphorylating the C-terminal domain of RNA polymerase II and activating other CDKs.
-
E.
CDK4
CDK4 is a cyclin-dependent kinase that regulates cell cycle progression and is a key therapeutic target in certain cancers.
- F. None of above.
- G. Unsure - the case is ambiguous/there is not enough information to decide.
Provenance (2 batches)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454d71b48190a1f80af9f82b6fcf |
completed | April 17, 2026, 2:35 p.m. |
| NER | Named-entity recognition | batch_69f1789a1fd08190bce5fa0babe695d3 |
completed | April 29, 2026, 3:18 a.m. |
Created at: April 17, 2026, 3:13 p.m.