Triple
T22690418
| Position | Surface form | Disambiguated ID | Type / Status |
|---|---|---|---|
| Subject | larotrectinib |
E561035
|
entity |
| Predicate | instanceOf |
P0
|
FINISHED |
| Object | breakthrough therapy |
C46686
|
CONCEPT FINISHED |
How this triple was built (1 step)
Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.
CD
Concept disambiguation
gpt-5-mini-2025-08-07
Target class: breakthrough therapy Context triple: [larotrectinib, instanceOf, breakthrough therapy]
-
A.
biologic therapy
Biologic therapy is a treatment that uses substances made from living organisms or their derivatives to target specific components of the immune system or disease processes.
-
B.
disease-modifying therapy
A disease-modifying therapy is a treatment that alters the underlying course or mechanisms of a disease to slow its progression, reduce long-term damage, or change its overall outcome rather than just alleviating symptoms.
-
C.
checkpoint inhibitor
A checkpoint inhibitor is a type of drug that blocks immune checkpoint proteins, thereby enhancing the immune system’s ability to recognize and attack cancer cells.
-
D.
orphan drug
An orphan drug is a pharmaceutical product developed specifically to diagnose, prevent, or treat a rare disease or condition that affects a small percentage of the population, often incentivized by special regulatory and financial benefits.
-
E.
Bruton tyrosine kinase inhibitor
A Bruton tyrosine kinase inhibitor is a targeted small-molecule drug that blocks BTK signaling in B cells to disrupt pathways critical for their activation, proliferation, and survival, primarily used in the treatment of certain B-cell malignancies and autoimmune diseases.
- F. None of above. chosen
Provenance (1 batch)
The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.
| Step | Stage | Batch ID | Status | When |
|---|---|---|---|---|
| creating | Elicitation | batch_69e2454d71b48190a1f80af9f82b6fcf |
completed | April 17, 2026, 2:35 p.m. |
Created at: April 17, 2026, 3:13 p.m.