Triple

T19245358
Position Surface form Disambiguated ID Type / Status
Subject INS gene E481234 entity
Predicate regulatedBy P86 FINISHED
Object NEUROD1 transcription factor NE NERFINISHED

How this triple was built (3 steps)

Every LLM step that produced this triple, in pipeline order — named-entity classification, the disambiguation choices (the exact options shown, with the pick highlighted), and the generated description. The batch + timestamp of each is in the Provenance table below.

NER Named-entity recognition gpt-5-mini
Instruction
Given a phrase, classify it is english named entity (e.g., persons, organizations, works of art) in Latin script, or not (e.g., literals, dates, URLs, verbose phrases). For disambiguation, the statement where the phrase occurs as object is also given. Please return a JSON object with `phrase` (string, the phrase being analyzed) and `is_ne` (boolean, indicating whether the phrase is a Named Entity).
Input
Phrase: NEUROD1 transcription factor | Statement: [INS gene, regulatedBy, NEUROD1 transcription factor]
NED1 Entity disambiguation (via context triple) gpt-5-mini-2025-08-07
Target entity: NEUROD1 transcription factor
Context triple: [INS gene, regulatedBy, NEUROD1 transcription factor]
  • A. Sox2
    Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
  • B. Notch intracellular domain
    The Notch intracellular domain is the cleaved, cytoplasmic fragment of the Notch receptor that translocates to the nucleus to regulate gene transcription in the Notch signaling pathway.
  • C. Wnt1
    Wnt1 is a highly conserved signaling protein in the Wnt family that plays a crucial role in embryonic development, cell fate determination, and oncogenesis in vertebrates.
  • D. c-Myc
    c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
  • E. TARDBP
    TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
  • F. None of above. chosen
  • G. Unsure - the case is ambiguous/there is not enough information to decide.
NED2 Entity disambiguation (via description) gpt-5-mini-2025-08-07
Target entity: NEUROD1 transcription factor
Target entity description: NEUROD1 transcription factor is a basic helix-loop-helix (bHLH) transcription factor crucial for neuronal differentiation and pancreatic beta-cell development, where it helps control insulin gene expression.
  • A. Sox2
    Sox2 is a key transcription factor that maintains stem cell pluripotency and self-renewal and is widely used in cellular reprogramming.
  • B. Notch intracellular domain
    The Notch intracellular domain is the cleaved, cytoplasmic fragment of the Notch receptor that translocates to the nucleus to regulate gene transcription in the Notch signaling pathway.
  • C. Wnt1
    Wnt1 is a highly conserved signaling protein in the Wnt family that plays a crucial role in embryonic development, cell fate determination, and oncogenesis in vertebrates.
  • D. c-Myc
    c-Myc is a proto-oncogene transcription factor that regulates cell growth, proliferation, and metabolism and is frequently dysregulated in cancer.
  • E. TARDBP
    TARDBP is a gene encoding the TDP-43 protein, a DNA/RNA-binding protein whose abnormal aggregation is a key pathological feature in amyotrophic lateral sclerosis and related neurodegenerative diseases.
  • F. None of above. chosen

Provenance (2 batches)

The batch behind each pipeline step, in order, with when it ran. Timestamps are batch-level — stages were processed in waves, so the object chain (NER → NED1 → NEDg → NED2) reads in order, but predicate / elicitation batches can sit in a different wave.

Step Stage Batch ID Status When
creating Elicitation batch_69d8e8cd9d1081908a181d02b88b59b8 completed April 10, 2026, 12:10 p.m.
NER Named-entity recognition batch_69e5fb2c34e88190a338e5a7ba906425 completed April 20, 2026, 10:08 a.m.
Created at: April 10, 2026, 1:27 p.m.